Possible role for lnterleukin-5 in asthma

Asthma is an allergic disease characterized by airway obstruction as a result of cellular accumulation due to the liberation of certain mediators. Among those mediators are the cytokines such as IL-5. lnterleukin-5 concentration has been estimated in 94 sera samples of Asthmatic patients in comparison with 41 non-asthmatic bronchitis as patient controls in addition to 30 apparent healthy control group using ELISA method. There is highly significant elevation of IL-5 in the asthmatic cases in comparison with healthy controls [P< 0.001]. We conclude that this cytokine may play the major role in asthmatic attack and it may be a good marker for the disease