Study on purification technology of patchouly oil with molecular distillation / 中国中药杂志

<p><b>OBJECTIVE</b>To establish an advanced purification techniques of the essential oils obtained from Pogostemon cablin.</p><p><b>METHOD</b>Molecular distillation (MD) was applied.</p><p><b>RESULT</b>Four distillates were obtained, chemical constituents of which were analyzed with GC-MS. Compared with those in original oils, the contents of active compounds (patchouli alcohol and pogostone) rose by 27%-47% in the distillates II and III.</p><p><b>CONCLUSION</b>Molecular distillation (MD) effectively raises the contents of patchouli alcohol and pogostone. The work is of great economic and scientific significance for the industrialization of P. cablin and the discovery of new drugs.</p>