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@#To investigate the relationship between red blood cell distribution width （RDW） and poststroke depression in patients with acute ischemic stroke. Methods Continuous collection of patients with acute cerebral infarction admitted to our hospital from May 2017 to May 2020.All cases were divided into the non PSD group and PSD group according to whether they were diagnosed with depression at 3 months. The clinical data of the patients were recorded，and RDW was detected by automatic five-classification blood cell analyzer in the morning of the second day after admission. Multivariate Logistic regression analysis were used to screen the risk factors of PSD.The ROC curve analysis was performed to evaluate the predictive value. Results A total of 413 eligible patients were included，with an average age of 65.89 years（aged 40 to 86 years） and 169 males （40.92%）.During the follow-up 3 months after onset，the total number of patients diagnosed with depression was 88例（21.31%）.Multivariate Logistic regression analysis showed that the admission NIHISS score（OR=1.134，95%CI1.049～1.225，P<0.001）and infarction of key areas（OR=1.363，95%CI 1.205～1.641，P<0.001），Female（OR=1.888，95%CI1.097～3.249，P=0.022）RDW（OR=3.730，95%CI 2.229～6.051，P<0.001）were independent risk factors for PSD. The area under the ROC curve （AUC） of RDW for predicting poor prognosis was 0.709（95%CI 0.656～0.763，P<0.001），the optimal cut-off value was 13.01%，the sensitivity was 77.6% and the specificity was 55.7%.Conclusion RDW was an independent risk factor for post stroke depression at 3 months in acute ischemic stroke patients.
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Objective To compare the three-dimensional （3D） gait characteristics of patients with medial meniscus injury of the knee before and after arthroscopic surgery. Methods Fifteen patients with medial meniscus injury and fifteen healthy subjects were included in the study. The 3D gait parameters were collected, including spatiotemporal parameters, kinematic parameters and kinetic parameters. Results (1) The preoperative walking speed and step length of the injury group were significantly lower than those of the control group. There was no significant difference in walking speed and step length after surgery between the injury group and the control group. (2) In the sagittal plane, the preoperative knee flexion-extension range of motion (ROM), the maximum flexion angle in load-bearing phase and swinging phase were significantly lower than those in the control group (P＜0.001). The maximum knee flexion in load-bearing response phase was significantly increased after surgery (P＜0.05), but the maximum flexion angle in swing phase and the knee flexion-extension ROM after surgery were still significantly lower than those of the control group (P＜0.05). In the coronal plane, the preoperative knee adduction-abduction ROM and the maximum adduction angle in gait cycle were significantly lower than those of the control group (P＜0.001). The postoperative parameters significantly increased compared with the preoperative ones (P＜0.05), but they were still significantly lower than those of the control group (P＜0.001). (3) In the sagittal plane, the postoperative first and second peaks of knee flexion moment in stance phase of the injury group increased, compared with the preoperative ones (P＞0.05), but they were still significantly lower than those of the control group (P＜0.05). In the coronal plane, the postoperative first and second peaks of knee adduction moment in stance phase of the injury group increased, compared with preoperative ones, but they were also significantly lower than those of the control group (P＜0.05). Conclusions Patients with medial meniscus injury have their own unique gait patterns, usually with stiffening gait to reduce the knee load. Arthroscopic meniscusplasty can significantly improve knee gait characteristics, but patients still cannot return to normal gait in a short period of time.
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Tibia shaft fracture is the most common long bone fractures clinically and intramedullary nail fixation is the best choice due to superior biomechanical characteristics for unstable tibia shaft fractures.At present,the common approaches for intramedullary nail insertion are divided into supra-patellar approach and infra-patellar approach.The semi-extended position of supra-patellar approach contributes to better fracture reduction but lead to potential patella-femoral cartilage injury.In contrast,flexion or hyper-flexion position of infra-patellar approach might result in unsatisfactory fracture reduction,then have an impact on clinical outcome.Therefore,the clinical outcome might be different because of approach choice.However,there is no consensus about the optimal surgical approach for intramedullary nailing.Thus,we performed the review to discuss the approaches for tibia intramedullary nailing and compare their strengths and weaknesses.