RESUMEN
Durante la niñez, la tromboembolia pulmonar (TEP) es una afección poco frecuente, aunque potencialmente mortal. El mayor número de episodios de tromboemblia venosa (TEV) es resultado de complicaciones de factores de riesgo subyacentes, tales como tumores malignos, quimioterapia (L-asparaginasa) y colocación de un catéter venoso central. Presentamos el caso de un paciente con leucemia linfocítica aguda y TEP que tuvo un presíncope y fue tratado satisfactoriamente con heparina de bajo peso molecular y antagonistas del calcio.
In childhood, pulmonary thromboembolism (PTE) is an uncommonbut potentially life-threatening disease. The greater numbers of venous thromboembolism (VTE) are complications of underlying risk factors such as malignancies, chemotherapy (L-asparaginase), and central venous catheter. We report a patient with acute lymphoblastic leukemia and PTE, who presented with near-syncope, and was successfully treated with low molecular weight heparin and calcium channel blockers.
Asunto(s)
Humanos , Masculino , Adolescente , Embolia Pulmonar/complicaciones , Embolia Pulmonar/tratamiento farmacológico , Bloqueadores de los Canales de Calcio/uso terapéutico , Factores de Riesgo , Resultado Fatal , Heparina de Bajo-Peso-Molecular/uso terapéutico , Leucemia-Linfoma Linfoblástico de Células Precursoras/complicaciones , Tromboembolia Venosa/complicaciones , Tromboembolia Venosa/tratamiento farmacológicoRESUMEN
Congenital extremity anomalies have many modes of presentation. Interruption of vascular supply with thrombophily is a rare cause of congenital extremity absence. Here it is presented a 7 mth old male with absence of the left lower extremity. Laboratory tests revealed Factor V Leiden and Prothrombin G20210A heterozygote mutation and that was as the cause of extremity absence. At the patients with congenital extremity absences, it is not imprudent to explore a possible thrombophilic mutation along with other known etiologic factors.
Asunto(s)
Enfermedades en Gemelos , Factor V/genética , Deformidades Congénitas del Pie/etiología , Humanos , Lactante , Pierna/anomalías , Masculino , Mutación Puntual , Trombosis/complicacionesRESUMEN
Glanzmann thrombasthenia is a qualitative platelet function disorder manifested by skin bleeds, epistaxis, gingival bleeding, gastrointestinal hemorrhage, hematuria, hemarthrosis, intracranial hemorrhage and visceral hematomas. We report a six day old newborn presenting with hematuria following suprapubic aspiration, who was diagnosed as Glanzmann thrombasthenia. We believe it to be the youngest case reported in the literature.