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Objective To systematically evaluate the risk of primary lung cancer in breast cancer patients. Methods A computer-based search was conducted for the English literatures about the risk of primary lung cancer in breast cancer patients in Medline, Scopus and Embase databases. Two researchers independently screened the literatures, extracted the data and assessed the risk of bias. The statistical analysis was performed using the Stata 15.5 software. Results A total of 7 references were included, and the overall risk of primary lung cancer in female breast cancer patients was slightly higher than that in the general population (SIR: 1.18, 95%CI: 1.09-1.27). Subgroup analysis showed that the risk of lung cancer was significantly increased in women aged < 50 years after diagnosis of breast cancer (SIR: 1.99, 95%CI: 1.48-2.69). Conclusion Compared with the general population, the risk of primary lung cancer is increased in female breast cancer patients, especially in young women with breast cancer.
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Objective To investigate the hysteroscopy application on uterine cavitary benign and its safety.Methods Two hundred and ten patients with benign lesions in the uterine cavity from Jan 2010 to Jan 2013 were selected as our subjects.They were underwent hysteroscopy and electric section,including 72 cases with uterine polyps resection,70 cases with uterine fibroids resection,and 68 cases with pregnancy tissue residue removal surgery.The follow up periods were 4 months to 2 years and the therapy effects were recorded.Results Two hundred and ten patients were got one successful operation.Operation period was ranged from 11 to 39 minutes and average was 15 minutes.The intraoperation bleeding volumes was ranged from 5 to 70 ml and no intraoperation complications occurred.During the follow-up periods,94.1％ (191/203) patients were recovered to regular menstruation and dysmenorrhea improvement rate was 87.70％ (178/203) at 1 month after operation.At 6 months after operation,96.1％ (195/203) and 91.6％ (186/203) patient were with the regular menstruation and dysmenorrhea improvement.Two cases with uterine cavitypolyp were reoccurred after operation and cured by electron section.Conclusion Hysteroscopy in treatment of benign uterine lesions is showed the satisfactory curative effect in terms of keep uterus integrity with little injury,slight pain.It is proved to be as the prefer methods to treatment for benign uterine cavity lesions.