A Case of Corneal Amyloidosis

Amyloidosis may be defined as a group of disorders of extracellular deposition of the fibrous protein amyloid in one or more sites of body with variable causes and pathogenesis which have in common characteristic histopathologic features. Primary localized corneal amyloidosis is confined in the cornea and has not the evidence of apparent preexisting disorder or systemic involvement. The incidence has been reported rare. We have experienced one case of corneal amyloidosis which is confirmed by the histopathologic evaluation. We report this rare case with literatures reviews.

A Statistical Observation on Transferred Ocular Perforation Injuries

The authors statistically analysed transferred patients among 110 ocular perforation injury patients who were admitted to the Seoul Paik Hospital between January 1, 1984 and December 31, 1988. Male was 85.9% and third decade was most common decades(30.5%). Left eye was more affected(59.8%) than right eye. The most common cause was traffic accident(37.%) and perforated site was corneo-sclera(43.%). Subconjunctival hemorrhage was the most common accompanied ocular manifestation(47.0%). Most of the perforated eyes were treated with primary closure of the wound. The final visual acuity was better in patients who were treated at only one hospital two or more hospitals before being transferred. With the above results, the final visual acuity may be related with the number of the hospital which the patients were treated before transferred.

The Laurence-Moon-Biedl Syndrome in a Family

Laurence-Moon-Biedl syndrome is a rare inherited disorder and its common findings include pigmentary retinal degeneration, obesity, hypogonadism, mental retardation and digital anomaly. Recently, the authors experienced two cases of Laurence-Moon-Biedl syndrome in a family of 15 year-old male and 17 year-old female. In our cases, the male patient showed syndactyly and polydactyly, chorioretinal degeneration, hypogonadism and female patient showed polydactyly, chorioretinal degeneration, hypogonadism, obesity and mental retardation.

An Experimental Study of the Corneal Epithelial Damage by Electric Welding Light on the Rabbit Cornea

The cellular alteration following the electric welding light on the rabbit corneal epithelial cells were studied in several conditions wearing various corneal contact lenses on the corneal surface exposed to the light for 5 minutes at 50 cm in each. The enucleated rabbit eyes 5 hours following the application of electric welding light were histopathologically investigated on the cellular structures of the cornea. The result were as follows: 1. The cellular alterations in a group of soft contact lens wearing consisted of multiple vacuole enlargement, separation of interdigitation and Desmosome, intracellular edema, and loss of organelles in superficial and wing cells layer. Loss of microvilli of the corneal superficial cells were observed. 2. Loss of cytoplasmic microorganelles and microvilli intercellular edema in superficial cell layer, and slight vacuoles enlargement in wing cells layer were demonstrated in a group of the direct light exposure group without contact lenses. 3. Loss of microvilli and intercellular edema with separation of interdigitation in superficial cell layer but no specific changes in wing cells layer were exhibited in a group of hard contact lens wearing. 4. The most destructive features of the corneal epithelial cells were observed in a group of soft contact lens wearing, and it was suggested that the doubtful effects of protection on the corneal superficial tissue in the case of soft contact lens wearing were noteworthy.