RESUMEN
PURPOSE: To evaluate the efficacy and need for boosting of mumps vaccine, we measured the degree of immunity of previously vaccinated healthy children with the age from 15 months to 15 years. METHODS: We measured mumps specific IgG & IgM antibody titers of 96 children, vaccinated at the age of 15 months, with the age from 15 months to 15 years by ELISA.(Enzyme linked immunosorbent assay) RESULTS: The results are as follows 1) Sixty three cases(65.6%) were positive for mumps IgG antibody and 18 cases (18.7%) were positive for IgM antibody. 2) Mumps IgG antibody decreased between the age of 4 to 6 years and after then increased again. CONCLUSIONS: We suggested that the boosting mumps vaccination will be required between the age of 4 to 6 years.
Asunto(s)
Niño , Humanos , Inmunoglobulina G , Inmunoglobulina M , Vacuna contra la Parotiditis , Paperas , VacunaciónRESUMEN
Pseudohypoparathyroidism is characterized by target cell resistance to the effects of parathyroid hormone and classified into various types depending on the phenotypic and biochemical findings. Pseudohypoparathyroidism type II differs from type I in that the urinary excretion of cAMP is elevated both in the basal state and after stimulation with PTH. We experienced a case of pseudohypoparathyroidism type II in 12year old man who had generalized seizure. He had hypocalcemia, hyperphosphatemia, elevated serum PTH level and urinary basal cAMP. Also he had a normal phenotypic appearance. Bilateral basal ganglia calcifications was detected by CT scan.
Asunto(s)
Ganglios Basales , Hiperfosfatemia , Hipocalcemia , Hormona Paratiroidea , Seudohipoparatiroidismo , Convulsiones , Tomografía Computarizada por Rayos XRESUMEN
Pseudohypoparathyroidism is characterized by target cell resistance to the effects of parathyroid hormone and classified into various types depending on the phenotypic and biochemical findings. Pseudohypoparathyroidism type II differs from type I in that the urinary excretion of cAMP is elevated both in the basal state and after stimulation with PTH. We experienced a case of pseudohypoparathyroidism type II in 12year old man who had generalized seizure. He had hypocalcemia, hyperphosphatemia, elevated serum PTH level and urinary basal cAMP. Also he had a normal phenotypic appearance. Bilateral basal ganglia calcifications was detected by CT scan.
Asunto(s)
Ganglios Basales , Hiperfosfatemia , Hipocalcemia , Hormona Paratiroidea , Seudohipoparatiroidismo , Convulsiones , Tomografía Computarizada por Rayos XRESUMEN
Drug-induced toxic epidermal necrolysis (TEN) is a bullous erythematous disease that is characterized by the appearance of scaled lesions and large sheets of pilling on the skin. A caseof TEN occured in a 10 month old female patient. The characteristic skin lesions of TEN developed after oral administration of carbamazepine for a partial seizure. Thig case consists of prodrome of malaise, fever, anorexia, and conjunctivity followed by erythema & flaccid bullae formation. Diagnosis was confirmed by histologic findings. This patient was treated with a massive systemic corticosteroid, antibiotics, fluid and electrolytes, and topical measures. Authors experienced an extremely rare case of TEN dur to carbamazepine, So report it with a brief review of literature.