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Chinese Journal of Radiological Health ; (6): 14-18, 2021.
Artículo en Chino | WPRIM | ID: wpr-973711

RESUMEN

Objective To investigate the status of radiological protection in Baoji City. Methods Using the questionnaire survey method, the survey forms were sent to the radiology clinics and other relevant units in the counties and districts of the city to investigate the basic situation of radiology and treatment of medical and health institutions, basic information of radiology and treatment equipment, personal information of radiation workers, and health monitoring of radiation workers. Results There is 1.13 X-ray diagnostic equipment per 10, 000 people, 0.015 radiotherapy equipment per 10, 000 people in Baoji City, and One million people own 11.4 CTs. There are 1, 102 radiation workers in Baoji City, and 2.92 per 10, 000 people. The occupational health check rate of medical radiation personnel was 87.7% within 2 years, the personal dose monitoring rate was 90.4%, the radiation worker training rate was 73.6% within 2 years, about the holding rate of "Radiation Staff Certificate" in Baoji City was 73.0%, and the occupational health file rate was 89.2%. The evaluation indexes of various health monitoring were lower, especially in township hospitals (35.7%~50.8%). Conclusion On the whole, the number of radiological diagnosis and treatment equipment is small, and Class A large equipment is almost blank. The city is stronger than the county in health monitoring. The status of health monitoring is very different from urban to rural areas.

2.
China Pharmacy ; (12): 2269-2274, 2020.
Artículo en Chino | WPRIM | ID: wpr-825660

RESUMEN

OBJECTIVE:To systematically evaluate the efficacy and safety of decitabine monotherapy in the treatment of myelodysplastic syndrome (MDS),and to provide evidence-based reference to the clinic. METHODS :Retrieved from Embase , Cochrane Library ,PubMed,Medline,Clinical Key ,Google Scholar ,CNKI,CBM and Wanfang data ,during the inception to Jun. 26th, 2020, randomized controlled trials (RCTs) about decitabine (decitabine group ) versus traditional combined chemotherapy(control group )in the treatment of MDS were collected. After literature screening and data extraction ,literature quality evaluation with bias risk evaluation tool recommended by Cochrane systematic evaluator manual 5.2.2,Meta-analysis was performed by using Rev Man 5.3 software. RESULTS :A total of 590 patients with 11 RCTs were included. Meta-analysis results showed that complete remission rate [OR =1.82,95% CI(1.23,2.70),P=0.003] and total response rate [OR =1.54,95% CI(1.05, 2.27),P=0.03] of decitabine group were significantly higher than those of control group ;the incidence of ADR [OR =0.26,95% CI(0.16,0.40),P<0.000 01],the incidence of infection [OR =0.48,95% CI(0.27,0.85),P=0.01] and the incidence of myelosuppression [OR=0.37,95% CI(0.17,0.81),P=0.01] in decitabine group were significantly lower than control group. The results of subgroup analysis according to the course of treatment showed that there was no significant difference in the complete remission rate and total response rate between 2 groups in the treatment course of 3 and 4 months(P>0.05);but there was significant difference in the treatment course of 1 month or 2 months,the decitabine group was significantly higher than control group(P<0.05). CONCLUSIONS:Decitabine has good efficacy and safety in the treatment of MDS patients ,and when the treatment time is less than or equal to 2 months,the complete remission rate and total response rate of decitabine in MDS lis1270755@163.com patients are better.

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