RESUMEN
75 patients were studied in Tauggyi, Shan State where chloroquine resistant falciparum malaria is prevalent. Response of the patients were followedup to 7 days for assessment, one group to chloroquine & another group to amodiaquine. In sensitive patients there was no difference in terms of fever and parasite clearence but in terms of treatment failures cholroquine was 48.8percent and amodiaquine was 20 percent.
Asunto(s)
Amodiaquina , Malaria FalciparumRESUMEN
Blood films from three different sites of the body of 56 patients were studied for malaria parasites. In the higher parasite density group the mean parasite count varies, the highest obtained from finger capillary blood, anticubital venous blood being intermediate and intradermal blood had the lowest count. The probable reason for this variation is discussed. In the lower parasite density group the mean speed in finding one parasite was statistically not significant in the three methods. Steps in performing intrademal blood letting is presented.
Asunto(s)
Malaria , Quinina , Resistencia a MedicamentosRESUMEN
Fifty-two patients with falciparum malaria during pregnancy were studied in Taunggyi, Shan States, Burma, during the period of April 1985 through December 1986. Severely ill cases were all treated with quinine, but uncomplicated cases were randomised to receive either quinine or amodiaquine. Fifty-one age-matched non-pregnant female patients were also randomised to receive either quinine or amodiaquine. All clinical and laboratory parameters were comparable between pregnant and non-pregnant group of patients. Falciparum malaria was most frequent among primigravidae, and occurred most frequently in the second trimester for all parities. There were no differences in parasite density, fever clearance and parasite clearance between groups with different parity or gestational period. Quinine and amodiaquine treatment were equally effective. The outcome of pregnancy with and without anti-malarial prophylaxis is discussed.