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China Journal of Chinese Materia Medica
; (24): 663-665, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-247414
RESUMEN
<p><b>OBJECTIVE</b>To investigate the effect of removing bacterial endotoxin in the key processes of Reduning injection.</p><p><b>METHOD</b>The content of bacterial endotoxins was detected by kenitic-turbidimetry and the removal efficacy was studied before and after using 0.8% of activated carbon and ultrafiltration with molecular weight cut-off of 10 x 10(3).</p><p><b>RESULT</b>The adsorption rate of bacterial endotoxins was 78.7% by using activated carbon, while the removal efficacy of bacterial endotoxins was 99.6% with ultrafiltration membrane at cut-off molecular weight 10 x 10(3).</p><p><b>CONCLUSION</b>The key technology can effectively guarantee the safety of Reduning injection.</p>