Role and mechanism of stabilizing microtubules of endothelial cells and pericytes in improving the microvasculature dysfunction after spinal cord injury / 解剖学报

Objective To explore the role and mechanism of stabilizing microtubules of endothelial cells and pericytes for ameliorating the dysfunction of microvasculature after spinal cord injury(SCI). Methods The endothelial cells and pericytes from rat brain microvascular tissue (microvessel) were separated and subjected to glucose oxygen deprivation (OGD). The cell viability was detected by CCK-8 and the expression of α-tubulin was detected by immunofluorescence and Western blotting. Rats (n = 36) were subjected to dorsal spinal cord transection at T

Reform and practice of clinical probation teaching based on "5+3" mode in clinical medicine / 中华医学教育探索杂志

Clinical novitiate is not only a significant part in the training of basic comprehensive ability of clinical medicine students,but also a weak link in current teaching practice link. This research is guided by the educational reform of the"5+3"talent training mode and it carries out reforms by constructing three-stage novitiate mode, realizing curriculum integration and PBL teaching as well as multi-dimensional performance appraisal etc.It is student-centered and lays emphasis on developing students' autonomous learning ability,basic clinical skills and thinking ability,so as to improve the training quality of the medical professionals and provide a referable novitiate teaching mode for the training of medicine professionals under the new situation.