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Chinese Journal of Virology ; (6): 382-385, 2013.
Artículo en Chino | WPRIM | ID: wpr-339941

RESUMEN

To gain more insights into epidemiologic characteristics and genotype of hantavirus in Apodemus agrarius in Changbai Area. Complete hantavirus S segment sequences were amplified by RT-PCR and sequenced. The phylogenetic trees were constructed for analysis of genetic characters of hantavirus. A total of 58 Apodemus agrarius were trapped in the epidemic areas, and complete hantavirus S segment sequences were obtained from 4 lung samples of these rodents (6. 90%0). Phylogenetic analysis of the four S segment sequences indicated that all viruses isolated from Apodemu sagrarius were closely related to genotype 6 of Hantaan virus (95. 8%-96. 3%, nucleotide identity; 98. 6%-99. 5%, amino acid identity), all of them had a specific S387 different from other genotypes of Hantaan virus.


Asunto(s)
Animales , Secuencia de Bases , China , Epidemiología , ADN Complementario , Química , Genética , Reservorios de Enfermedades , Virología , Genotipo , Orthohantavirus , Clasificación , Genética , Infecciones por Hantavirus , Epidemiología , Virología , Pulmón , Virología , Murinae , Virología , Filogenia , ARN Viral , Genética , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Enfermedades de los Roedores , Virología , Análisis de Secuencia de ADN , Proteínas Virales , Genética
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