Transforming of the drug resistance plasmid from Staphylococcus aureus into Escherichia coli / 南方医科大学学报

<p><b>OBJECTIVE</b>To discuss the possible mechanism of drug resistance transmission between Staphylococcus and Escherichia coli.</p><p><b>METHODS</b>The chloramphenicol resistance plasmid of Staphylococcus aureus was extracted to transform the sensitive Escherichia coli, and the drug-resistant Escherichia coli were screened by drug sensitivity test.</p><p><b>RESULTS</b>The drug-resistant Escherichia coli were successfully obtained.</p><p><b>CONCLUSION</b>Staphylococcus may have a natural shuttle plasmid of drug resistance, which can transform Escherichia coli under specific conditions.</p>