RESUMEN
Objective To assess systematically the effect of (cognitive behavior therapy,CBT) on PANSS of schizophrenia.Methods Relative literature was searched by computer at home according to the inclusion and the exclusion criteria,which were analyzed by RevMan5.2 software,and literature selection and repetition were used according to the Note Express software.Results A total of 11 studies were brought into the study.According to the different time of intervention,the results showed that,the cognitive behavior therapy intervention continued for 2 months,I2 was 80％,the statistical result of random effects model analysis was [SMD=-0.64,95％CI (-1.14～-1.13),P＜0.05]; the cognitive behavior therapy intervention continued for 6 months,I2 was 64％,the statistical result of random effects model analysis was [SMD=-0.40,95％CI (-0.71,-0.08),P＜0.05]; the cognitive behavior therapy intervention continued for 12 months,the statistical result of fixed effects model analysis was[MD=-5.65,95％CI(-6.20,-5.09),P＜0.01].The replacement of statistical models for the sensitive analysis showed that the result was stabile and reliable.Conclusions The cognitive behavior therapy may reduce PANSS of patients with schizophrenia,But because the influence of some factors,the time of intervention is limited,so the result of this research is that the best intervention time for clinical symptoms improvement is from 6 months to 1 year.