A Case of Darier Disease with Typical Nail Changes / 대한피부과학회지

Darier disease is a rare genodermatosis clinically characterized by multiple hyperkeratotic papules and plaques predominantly on seborrheic areas. It has characteristic histopathological features; corps-ronds, grains, suprabasal clefts or lacunae, villi projections etc. We present a case of Darier disease in a 36-year-old woman. She had suffered from skin lesions which bore a great resemblance to those of verruca plana or eruptive syringoma. We could confirm the diagnosis as Darier disease because she had the characteristic nail changes.

A Case of Basaloid Follicular Hamartoma Combined with Basal Cell Epithelioma / 대한피부과학회지

Basaloid follicular hamartoma(BFH) is a rare, benign adnexal tumor with a wide clinical appearance spectrum. A characteristic finding is multifocal islands in the papillary dermis and branching cords of basaloid epithelial cells in continuity at various sites with the basal layer of the epidermis and the hair follicles. We present a case of basaloid follicular hamartoma combined with basal cell epithelioma that developed on the tip of the nose in a 75-year-old man. To our knowledge, this is the first case report of basaloid follicular hamartoma combined with basal cell epithelioma in the Korean literature.

A Case of Callus Induced By Tophi / 대한피부과학회지

Callus is a nonpenetrating circumscribed hyperkeratosis produced by repeated friction or pressure. It occurs on parts subjected to intermittent pressure, particularly on the palms and soles, and particularly over the bony prominences of the joints. In painful callosities of the feet, ill-fitting shoes and orthopedic problems of the foot (bunions, exostoses) are some of the etiological factors to be considered. Gout is a condition of inborn metabolic and/or acquired form of the disease characterized by hyperuricemia, tophaceous deposits of sodium urate and recurrent attacks of arthritis. We present a case of callus caused by tophi. The patient was a 45-year-old man who had complained of a painful, well-demarcated, hyperkeratotic plaque on the heel of the left foot for 18 months. After the tophi beneath overlying whitish thickened skin had been removed, the skin lesion disappeared and to date has not recurred.

A Case of Multiple Glomangioma showing Some Foci of Leiomyoma / 대한피부과학회지

We report an unusual case of multiple glomangioma showing the histopathologic findings of focal leiomyomatous component. A 23-year-old man complained of multiple, bluish, soft nodules, 0.5 to 2cm in diameter, which were distr ibuted on the back and both upper limbs. Histologic examination revealed some foci composed of spindle-shaped smooth muscle cells with abundant eosinophilic cytoplasm and blunt ended nuclei as well as cells with features intermediate between glomus cells and fully differentiated myocytes. It was confirmed by immunohistochemical and ultrastructural studies.