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1.
Kosin Medical Journal ; : 84-89, 2017.
Artículo en Inglés | WPRIM | ID: wpr-149279

RESUMEN

Protein losing enteropathy (PLE) due to systemic lupus erythematosus (SLE) is relatively uncommon. PLE may be appeared sequentially after the diagnosis of SLE or concurrently with SLE. In most of concurrent cases, PLE was diagnosed one of various symptoms of SLE. Cases of PLE as the initial and only clinical presentation of SLE have been rarely reported. We described a 30-year old woman with general edema and abdominal distension was diagnosed PLE after stool alpha 1 antitrypsin clearance test. Her symptoms were getting worse even though the treatment with intravenous albumin. She was finally diagnosed PLE associated with SLE by additional laboratory findings (positive antinuclear antibody and anti-dsDNA IgG and low C3, C4 and CH50). She was treated with high dose of steroids and her symptoms were improved.


Asunto(s)
Femenino , Humanos , alfa 1-Antitripsina , Anticuerpos Antinucleares , Diagnóstico , Edema , Inmunoglobulina G , Lupus Eritematoso Sistémico , Enteropatías Perdedoras de Proteínas , Esteroides
2.
Infection and Chemotherapy ; : 268-271, 2015.
Artículo en Inglés | WPRIM | ID: wpr-92658

RESUMEN

Brucellosis is a multisystem disease with various clinical symptoms. Neurobrucellosis is a rare but serious manifestation of brucellosis. A 60-year-old man with a previous diagnosis of brucellar spondylitis presented with sudden onset of aphasia and numbness of the right upper extremity. Cerebral angiography showed diffuse narrowing and dilatation on the distal branches of both the anterior cerebral artery (ACA) and the left middle cerebral artery (MCA) which indicated cerebral vasculitis, and the patient's Brucella agglutinin titer was 1:1280. After combined antimicrobial and steroid therapy was started, the patient's condition improved significantly, and he was discharged after 1 month. Antimicrobial therapy was continued for 16 months on an outpatient basis, and the last Brucella agglutinin titer was 1:40. To our knowledge, this is the first case of relapsed neurobrucellosis with vasculitis in Korea to have been treated successfully.


Asunto(s)
Humanos , Persona de Mediana Edad , Arteria Cerebral Anterior , Afasia , Brucella , Brucelosis , Angiografía Cerebral , Diagnóstico , Dilatación , Hipoestesia , Corea (Geográfico) , Arteria Cerebral Media , Pacientes Ambulatorios , Espondilitis , Extremidad Superior , Vasculitis , Vasculitis del Sistema Nervioso Central
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