Two new compounds from Hypericum sampsonii / 中草药

To study the chemical constituents in the aerial parts of Hypericum sampsonii. Chromatographic methods were used for the isolation and purification. The structures were identified on the basis of spectroscopic analysis. Four compounds were isolated from the 60% ethanol extract in the aerial parts of H. sampsonii. They were identified as 3', 5'-dihydroxy-2, 4, 6-trimethoxylbenzophenone (1), 3'-hydroxy-2, 4, 6-trimethoxylbenzophenone-5'-O-α-L-rhamnopyranoside (2), 2-hydroxy-4, 6-dimethoxylbenzophenone (3), and 2, 4, 6, 3', 5'-pentamethoxylbenzophenone (4). Compounds 1 and 2 are two new benzophenone compounds named sampsine A and sampsine B; Compounds 3 and 4 are isolated from H. sampsonii for the first time.