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With the continuous deepening of public hospital reform and implementation of internal control systems in China, comprehensive evaluation of the implementation effect of internal control systems in public hospitals is gaining greater weight. To explore the comprehensive evaluation method for such aspect, the authors selected 31 indexes in 6 dimensions based on the analysis of evaluation indexes to construct a comprehensive evaluation index system. The Delphi method was used to determine the relative weight of each evaluation index, and a fuzzy comprehensive evaluation model for the implementation effect of the internal control system in public hospitals was constructed. This paper conducted an application study on the comprehensive evaluation of the implementation effect of the internal control system in a hospital in Suzhou to verify the effectiveness of the model, and a comprehensive evaluation of the implementation effect of the internal control system in the public hospital was implemented. These efforts provided an effective management method for analysis of the implementation effect of the internal control system in public hospitals.
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The paper analyzed the internal causes of the corruption risk control mechanism at public hospitals in China. Based on the current development of such mechanism, the authors proposed such measures as pre-warning, intermediate supervision and follow-up actions against the corruption risk exposure commonly found at such hospitals. These efforts aim at further improvement of the corruption risk control of the hospitals.
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Objective To explore the difference of autobiographical memory (AM) between depressive patients with and without alexithymia,and correlation between AM and alexithymia in depressive patients with alexithymia.Methods 29 depressive patients with alexithymia,34 depressive patients without alexithymia were enrolled.All patients were measured by autobiographical memory test (AMT),Toronto alexithymia scale-20 (TAS20),Hamilton depression scale-24 (HAMD-24).Results ①The negative overgeneral AM score was higher in depressive patients with alexithymia than those without alexithymia ((3.34± 1.80),(2.51 ± 1.12),respectively t=2.19,P＜0.05).②The total overgeneral AM score was higher in depressive patients with alexithymia than those without alexithymia ((6.14±2.44),(4.86±2.06),respectively t=2.21,P＜0.05).③)The correlation coefficient (r value) between the total score of overgeneral AM and total score of TAS,TAS-Ⅲ scores of TAS in depressive patients with alexithymia were significantly positively correlated (r=0.240～0.611,P＜0.05).However,the correlation coefficient between the total score of specific AM and total score of TAS,TAS-Ⅲ scores of TAS in depressive patients with alexithymia were significantly negatively correlated(r=-0.502～-0.205,P＜0.05).Conclusion Compared with depressive patients without alexithymia,the overgeneral AM in depressive patients with alexithymia is more severe,and the alexithymia can increase the severity of overgeneral AM.
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Peanut is one of the most popular foods in the world due to its high nutrition; however, it contains multiple seed storage proteins which are identified as allergens and hence are the most common cause of life-threatening, IgE-mediated anaphylaxis among the hypersensitive individuals. Three peanut proteins, Arachis hypogaea allergy 1, 2, 3 (Ara h 1, Ara h 2 and Ara h 3), which have the common biochemical characteristics like resistance to proteases and heat, are considered as the major allergens because they are recognized by serum IgE from a peanut-allergic patient population. The linear IgE-binding epitopes in the allergens lay the foundation of the anaphylaxis in the peanut-allergic individuals. Peanut allergy is often a life-long problem, so many investigators are focusing on decreasing clinical reactivity. In this review, the latest advances in the researches on biochemical characteristics, structure and function of the three major allergens were described and particular attention was given to the immunity properties of the three allergens. The future research directions were also discussed.
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Animales , Humanos , Albuminas 2S de Plantas , Química , Genética , Alergia e Inmunología , Antígenos de Plantas , Química , Genética , Alergia e Inmunología , Arachis , Química , ADN , Genética , Glicoproteínas , Química , Genética , Alergia e Inmunología , Inmunoglobulina E , Genética , Proteínas de Plantas , Química , Genética , Alergia e InmunologíaRESUMEN
Objective: To study the antioxidant activity of Clematis chinensis Osbeck polysaccharide(CCP).Methods:① To assay the scavenging activity of CCP on hydroxyl radical and superoxide anion in vitro.② To analyze the effect of CCP on red blood cell autoxidation hemolysis induced by H2O2 by colorimetry.③ To study the effect of CCP on acute hepatic injury of the mice induced by carbon tetrachloride.Results: CCP could eliminate the hydroxyl free radical and the superoxide anion free radical,reduce red blood cell autoxidation hemolysis induced by H2O2,raise the activities of SOD and GSH-Px in hepatic injury mice's serum and liver apparently,reduce the content of MDA and liver index notably.Conclusion: CCP has the significantly action of anti oxidation activity in vitro and in vivo which relates to removing oxygen free radical.