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Journal of Breast Cancer ; : 218-221, 2016.
Artículo en Inglés | WPRIM | ID: wpr-166628

RESUMEN

Women with BRCA1/2 mutations have a high risk of breast cancer and may opt for risk-reducing mastectomy (RRM). We report a 38-year-old Japanese woman who was diagnosed as a BRCA2 mutation carrier. She underwent prophylactic bilateral skin-sparing mastectomy (SSM) with excision of the nipple and preservation of the areola skin. It is unclear whether a bilateral RRM leads to better survival compared with intensive surveillance. The oncological risk associated with the presence of remnant breast glandular tissue after SSM or nipple-sparing mastectomy has been obscure. We report the first case of RRM for a Japanese BRCA mutation carrier and provide a literature review on risk management for BRCA mutation carriers with a focus on the concepts and procedures of RRM.


Asunto(s)
Adulto , Femenino , Humanos , Pueblo Asiatico , Mama , Neoplasias de la Mama , Mastectomía , Mastectomía Subcutánea , Pezones , Procedimientos Quirúrgicos Profilácticos , Gestión de Riesgos , Piel
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