Nutritional risk and malnutrition in patients with gastrointestinal malignant tumors in day wards:a cross-sectional analysis / 肠外与肠内营养

Objective:This study investigated the nutritional risk and malnutrition of patients with digestive system malignant tumors in the day ward and evaluated the risk of comorbidity with nutritional risk and the risk factors of malnutrition in this population.Methods:A cross-sectional study was conducted to collect patients with malignant tumors of the digestive system who were admitted to the day ward of our hospital from November 23,2020,to December 14,2020.The Nutritional Risk Screening Form(NRS 2002)was used for nutritional risk screening,and the Subjective Assessment of Overall Nutritional Status(PG-SGA)was used to assess malnutrition,to investigate nutritional risk and prevalence of malnutrition,and to analyze potential influencing factors.Results:Among the 464 patients with malignant tumors of the digestive system in the day ward,the incidence of nutritional risk was 26.9％,the incidence of malnutrition was 34.7％,and the incidence of severe malnutrition was 14.2％.Multivariate analysis showed that patients with Karnofsky Performance Status(KPS)score＜90 and hypoproteinemia were more likely to have nutritional risk(P＜0.05).Patients with KPS score＜90 and chemotherapy cycles＞6 were more likely to be malnourished(P＜0.05).Conclusions:Digestive system malignant tumor patients in the day ward still have a high proportion of nutritional risks and malnutrition.For patients with KPS score＜90,hypoalbuminemia,and chemotherapy cycles＞6,nutrition issues should be given special attention.

Review and Prospects of Pathogen Detection Related to Autopsy of Coronavirus Infectious Diseases / 法医学杂志

In the past, coronavirus caused two serious human-to-human pandemics in the world, including severe acute respiratory syndrome （SARS） and Middle East respiratory syndrome （MERS）. In late 2019, coronavirus disease 2019 （COVID-19） caused another major global public health event. Due to the strong infectivity of novel coronavirus, it is difficult to carry out the autopsy of related death cases widely. This paper reviews the previous status of the pathogen detection related to the autopsy of coronavirus infection diseases, and introduces the ongoing detection methods of novel coronavirus in clinical practice, in order to provide reference for the pathogen detection and study related to autopsy of COVID-19.

Application Prospects of Virtual Autopsy in Forensic Pathological Investigations on COVID-19 / 法医学杂志

Autopsy of patients who died of infectious diseases is of significance for public health management. Few forensic autopsies have been performed since the outbreak of the corona virus disease 2019 （COVID-19） due to some limitations, thus forensic pathological examination failed to contribute to the prevention and treatment of infectious diseases. Virtual autopsy has unique advantages in the forensic examination of patients who died of infectious diseases. Accumulated virtual autopsy image data are of great value to the study of the pathological mechanism and diagnosis of COVID-19. This article reviews the relationship between imaging changes and pathology of the COVID-19 as well as the application of virtual autopsy in autopsy of patients who died of infectious diseases, in order to provide reference for performing virtual autopsy in the outbreak of COVID-19.