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Recently, single cell RNA sequencing (scRNA-seq) technology has enabled the discovery of novel or rare subtypes of cells and their characteristics. This technique has advanced unprecedented biomedical research by enabling the profiling and analysis of the transcriptomes of single cells at high resolution and throughput. Thus, scRNA-seq has contributed to recent advances in cardiovascular research by the generation of cell atlases of heart and blood vessels and the elucidation of mechanisms involved in cardiovascular development and diseases. This review summarizes the overall workflow of the scRNA-seq technique itself and key findings in the cardiovascular development and diseases based on the previous studies. In particular, we focused on how the single-cell sequencing technology can be utilized in clinical field and precision medicine to treat specific diseases.
RESUMEN
PURPOSE: The aim of this study was to identify the sexual desire, sexual attitude and sexual desire coping behavior in military personnel, and analyze relationships among these variables. METHODS: Data were collected from February to April, 2015 using a structured questionnaire. Participants in the study were 199 military personnel visiting the military hospital P. RESULTS: The average score for sexual desire was 2.09±0.59, for sexual attitude, 3.15±0.42, and for sexual desire coping behavior, 3.18±0.40. Sexual desire showed a significant difference according to age (F=3.386, p=.023), assignment (F=3.327, p=.038). Sexual attitude was significantly different by religion (F=6.857, p<.001). The sexual desire coping behavior was found to be more active with military service period 5~9 months compared to 11~15 (F=3.621, p=.014) and in private first class compared to rank of private (F=3.165, p=.026). There was a significant positive correlation between sexual desire and sexual behavior, between sexual attitude and sexual desire coping behavior. CONCLUSION: To prevent sex-related accidents and diseases, it is necessary to provide sexual and health education customized for military personnel. For military personnel to cope appropriately with sexual desire, military personnel need to implement alternate measures such as encouraging soldiers to enjoy hobbies or physical exercise programs.