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Objective To explore the clinical value of real -time ultrasound elastography in the diagnosis of thyroid nodules , and to provide reference for the clinical diagnosis and treatment of patients with thyroid nodular lesions.Methods The clinical data of 62 patients with thyroid nodule occupying lesions were retrospectively analyzed.The results of real-time ultrasound elastography imaging and pathological diagnosis were compared ,and the accuracy ,sensitivity and specificity of real -time ultrasound elasticity imaging in the diagnosis of thyroid nodular lesions were analyzed.Results The patients with elastic grade 0,pathological examination showed follicular adenoma cystic degeneration;The patients with elastic gradeⅠ,pathological examination showed follicular hyperplastic nodules ;The patients with elastic grade Ⅱ,pathological examination showed follicular gland tumor;The patients with elastic grade Ⅲ,pathological examination showed papillary adenocarcinoma;The patients with elastic grade Ⅳ,pathological examination showed papillary adenocarcinoma .In patients with elastic grade 0,3 patients had proliferative nodules , and 5 cases were follicular adenomas .Among the patients with grade Ⅰ,5 cases were proliferative nodules ,8 cases were follicular adenoma ,1 case of papillary adenocarcinoma;of gradeⅡpatients,6 cases of proliferative nodules ,14 cases of follicular adenoma ,2 cases of papillary adenocarcinoma .Among the patients with grade Ⅲ,4 cases were follicular adenomas,and 6 cases were papillary adenocarcinomas .Among the patients with grade Ⅳ,3 cases were follicular adenomas,7 cases were papillary adenocarcinomas .The diagnostic accuracy of real -time ultrasound elastography was 93.5%,and the difference was not statistically significant (P>0.05).The sensitivity and specificity of real -time ultrasound elastography were 100.0% and 72.6%.Conclusion Real -time ultrasound elastography has high accuracy in the diagnosis of benign and malignant lesions of thyroid nodules ,it is worthy of being widely promoted .
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Objective To discuss the application of cystic cavity flushing technique in percutaneous ethanol sclerotherapy for the thyroid colloid cysts.Methods A total of 49 patients with thyroid colloid cysts were randomly divided into the study group (n=33) and the control group (n=16).Patients in the study group received cystic cavity flushing treatment by using saline together with α-chymotrypsin,which was followed by percutaneous ethanol injection (PEI).Patients in the control group underwent simple aspiration of cyst fluid followed by PEI.The residual cystic volume,the effective rate and the untoward effects were calculated at one,3 and 6 months after the treatment,and the results were compared between the two groups.Results Striking difference in the changes of postoperative residual cystic volume existed between the study group and the control group.The effective rate of PEI in the study group was 93.9％,which was obviously better than 68.8％ in the control group,the difference between the two groups was statistically significant (P＜0.05).No untoward effect was observed during the performance of aspiration of cyst fluid and flushing of cystic cavity.Nevertheless,bad side effect occurred in PEI procedure in both the study group (6.1％) and the control group (8.3％),but the difference was not statistically significant (P=0.75).Conclusion For the treatment of thyroid colloid cysts,the use of aspiration of cyst fluid together with cystic cavity flushing technique by using saline combined with α-chymotrypsin is safe and reliable,it can improve the curative effect of subsequent PEI.