[Assessment of liver pathological alterations in yellowfin seabream [Achantopagrus latus] and Abu mullet [Liza abu] in Musa creek in response to petrochemical pullutants]

Musa creek, suitable place for spawning of many fish species and other organisms, is one of the most important and voluble ecosystems in the west of Iran that received so many attentions due to existents of various industries around this part of Persian Gulf. Previous studies confirmed that marine fish have collected high amounts of pollutants in this area which could be lead to sever tissue changes in these fish. In the present study, pathological alterations of liver is used for evaluating of contaminants effects on two fish species including of yellowfin seabream and abu mullet in Musa creek. In this study, 50 yellowfin seabreams and 50 abu mullets were collected from five sampling sites in Mussa creek including: 1. Petrochemical, 2. Gaafari, 3. Magidieh, 4. Ghazaleh and 5. Zangi. The samples were taken from the liver after fish dissection and were fixed in bouin's solution. The liver samples were then studied based on the routine histological methods. The pathological changes in the liver included vacuolation of hepatocytes, nuclear hypertrophy, focal necrosis, dilation of sinusoid and diss spaces. The amount of histopathological alteration index [HAI] for liver of both species was significantly higher at the Petrochemical station than other sites [p<0.05]. The least amount of HAI was related to Zangi station. The results of present study showed that the alternations of liver tissue structure in Achantopagrus latus and Liza abu caused by the Musa creek contamination and there is close relation between amounts of this alterations and the environmental pollution

[ case report of HIN1 pneumonia in a patient with systemic lupus erythematosus]

Infections are one of the leading causes of morbidity and mortality in systemic lupus erythematosus [SLE] patients. The immunosuppressed patients might be at risk for serious influenza-associated complications. In this case report, a man with severe novel H1N1 pneumonia with no mortality and a good prognosis is introduced. A 37-year-old man with a medical history of SLE, antiphospholipid syndrome, cerebrovascular accident and recurrent deep venous thrombosis presented with complaints of the rapid progressive fever, severe dyspnea, productive cough and progressive hemoptesis admitted to Kashan Shahid-Beheshti hospital in November 2009. The chest x-ray revealed a bilateral alveolar infiltration. Based on epidemiological evidence among some hospitalized patients compatible with H1N1 influenza as well as their unresponsiveness to antibiotic therapy, a nasopharyngeal specimen was obtained for RT-PCR and treatment with broad-spectrum antimicrobial agents and Oseltamivir was started. After 4 days of antiviral treatment, fever was removed and dyspnea was decreased. Moreover, RT-PCR was positive for H1N1 and after 10 days the patient was discharged with a good condition. According to the results, prompt diagnosis and treatment of H1N1 pneumonia in an immunosuppressed condition can prevent the morbidity and mortality of disease

[Epidemiological survey of confirmed influenza A [H1N1] in Kashan, Aran and Bidgol cities during 2009-10]

The first outbreak of Influenza A [H1N1], the first pandemic influenza in the present century, in Iran was in Kashan in July 2009. This study was carried out to describe the stages of spread and also the outcome of influenza A [H1N1] in terms of incidence and death in Kashan, Aran and Bidgol cities during 2009-10. In this case series-study of confirmed influenza A [H1N1], clinical and demographic data of all confirmed cases were recorded using SPSS software and were analyzed by Mann-Whitney test. The total number of confirmed cases [mean and median of age were 29.8 +/- 18.7 and 26 years, respectively] was 86 with a male/female ratio of 1:1. Among the 7 cases who died [mortality rate: 8.1%] the mean age for death was 46.9 +/- 27.9 years, though greater than that of the recovered cases [30.01 +/- 18.1 years], but non-significant statistically. Beginning of new educational year for schools was identified as the most important factor in spread of the disease. Considering the mortality rate and other related variables, no significant difference was seen between Kashan, Aran and Bidgol cities compared to other countries. However, comparing the present findings with the findings of other domestic medical universities can disclose the reasons for disparities. Moreover, a 10 week time interval between the first outbreak and the peak for pandemy highlights the presence of an efficient surveillance system for disease control