Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
Añadir filtros








Tipo de estudio
Intervalo de año
1.
Saudi Medical Journal. 1995; 16 (1): 13-16
en Inglés | IMEMR | ID: emr-114553

RESUMEN

Qatif is an area with a high prevalence of haemoglobinopathies mainly thalassaemia and sickle cell anaemia. The purpose of this study is to analyse the clinical features and result of treatment of children with beta thalassaemia. Paediatric department of Qatif Central Hospital. 20 children with beta thalassaemia aged 12 years or younger [8 boys and 12 girls] followed up regularly in the haematology clinic over a period of 6 years [1988-1993]. Their age range is 18 months to 12 years [median, 8 years] and the age range at the first blood transfusion was 6 to 48 months [median, 18]. Physical evaluation revealed that weight was below the 10[th] percentile in 12 patients [60%], height was below the 10[th] percentile in six patients [30%], liver sizes were more than 2 cm below costal margin [BCM] in ten patients and more than 4 cm BCM in seven patients. Four patients had splenectomy, three patients had a spleen less than 2 cm BCM and 13 patients had a spleen more than 2 cm BCM. Cardiac evaluation by EKG and chest x-ray revealed cardiomegaly in five patients [25%]. Evaluation of iron overload by serum ferritin estimation was above 1000 mg/ml in 17 patients [85%]. Liver enzymes were high in 18 patients [90%]. Screening for hepatitis surface antigen and HIV one-two were negative in all cases. This study indicates that children with beta thalassaemia major in Qatif tend to have severe complications due to inadequate treatment, and great efforts are needed to improve the medical care provided to this group of patients if we are to give them a real chance for life


Asunto(s)
Humanos , Masculino , Femenino , Anemia/diagnóstico
2.
Saudi Medical Journal. 1995; 16 (3): 210-212
en Inglés | IMEMR | ID: emr-114592

RESUMEN

To determine the effect of glucose-6-phosphate dehydrogenase deficiency on the incidence and types of neonatal septicaemia. Retrospective review of the charts of cases of neonatal septicaemia. Babies with culture proven septicaemia between January 1989 and December 1990. Subjects were stratified into glucose-6-phosphate dehydrogenase normal [Group one] and deficient [Group two]. The two groups were compared. Of the 100 charts reviewed 80 were G-6-PD normal [Group one], while 20 were G-6-PD deficient [Group two]. In Group one and Group t 36 [45%] and nine [45%] babies were premature respectively. Early neonatal septicaemia was found in 24 [30%] babies in Group one, and in five [25%] babies in Group two, while late onset septicaemia was found in 56 [70%] babies and 15 [75%] babies in Group one and Group two respectively [p>0.5]. In Group one, 69 [86.3%] babies had catalase-positive organisms, compared with 18 [90%] babies in Group two, [p>0.5]. Nineteen [23%] babies died in Group one, while five [20%] babies died in Group two [p>0.5]. G-6-PD deficiency is neither associated with increased risk of neonatal septicaemia, nor with higher risk of acquiring infections with catalase-positive organisms


Asunto(s)
Humanos , Enfermedades del Recién Nacido/etiología
3.
Bahrain Medical Bulletin. 1993; 15 (1): 31-4
en Inglés | IMEMR | ID: emr-27318

RESUMEN

An 8-month old Saudi Arabian boy presented with Diamond Blackfan Anaemia [DBA] and polydactyly. He required support with monthly red blood cell [RBC] transfusions. Although his bone marrow showed erythroblastopenia with giant pro-erythroblasts, examination of a later serum sample showed no evidence of B19 parvovirus DNA, and significant amounts of IgM and lg ti-B19 antibodies. He showed no clinical improvement on a 3-month course of prednisone alone, subsequently followed by concomitant oxymethalone for 5 months. However, a 9 day course of daily infusion of anti lymphocyte globin [ALG] was followed by a significant improvement in haemoglobin. Although he briefly suffered a relapse about 9 months later, he recovered spontaneously and has been in complete remission since. We conclude that some patients with DBA may benefit from treatment with ALG


Asunto(s)
Masculino , Suero Antilinfocítico , Transfusión Sanguínea , Análisis Químico de la Sangre , Anemia de Fanconi/etiología , Ciclofosfamida
4.
Bahrain Medical Bulletin. 1992; 14 (2): 65-66
en Inglés | IMEMR | ID: emr-23192

RESUMEN

This is a report of a 6 year old Saudi girl with the rare syndrome of cortical hyperostosis. She had the typical clinical and radiological findings of the disease. In addition, she had unusual long standing history of pseudoparalysis of the lower limbs, failure to thrive and recurrent epistaxis


Asunto(s)
Informes de Casos
5.
Annals of Saudi Medicine. 1990; 10 (5): 521-4
en Inglés | IMEMR | ID: emr-121784

RESUMEN

The purpose of this study was to analyze the clinical features of and results of treatment in pre-school Saudi children [< 6 years of age] with Hodgkin's disease. The subjects were 34 patients [28 boys and 6 girls; male to female ratio, 4.7:1] seen at King Faisal Specialist Hospital and Research Centre [KFSH and RC] over a period of 14 years [1975 to 1989]. The age range at the time of presentation was 18 to 66 months [median, 42]. Presenting complications included lymphadenopathy in 33 patients, anemia in 15, and fever in 13. Histological subjects included mixed cellularity in 22 patients [65%], nodular sclerosis in ten [29%], and lymphocyte depletion and lymphocyte predominance in one patient each [2.9%]. The distribution of the patients among the clinical stages at presentation was as follows: Stage I, six patients [18%]; Stage II, ten patients [29%]; Stage III, 15 patients [44%]; and Stage IV, three patients [9%]. Twenty-nine patients underwent chemotherapy and only four patients had radiotherapy; one patients received both. Nineteen patients [56%] survived disease-free from 8 to 135 months [median, 48 months], four suffered relapse and underwent alternate therapy, two died, and nine were lost to follow-up. The childhood Hodgkin's disease in per-school children seen in our study tended to be more advanced at diagnosis and the mixed cellularity form was predominant. The methods of treatment were tolerated without serious side effects and the overall therapeutic response was good


Asunto(s)
Preescolar
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA