Perfiles de salud en pacientes con enfermedades crónicas en una institución de salud de alta complejidad / Health profiles in patients with chronic diseases in a high-complexity health institution / Perfis de saúde em pacientes com doenças crônicas numa instituição de saúde de alta complexidade

Objetivo: describir los diferentes perfiles, en términos de calidad de vida relacionada con la salud, en pacientes con enfermedades crónicas en una institución de salud de alta complejidad. Metodología: estudio transversal descriptivo. Se evaluó la calidad de vida relacionada con la salud mediante el instrumento EQ-5D en pacientes con enfermedades crónicas que consultaron a medicina interna y sus subespecialidades, en el servicio de consulta externa de una institución de salud de alta complejidad de la ciudad de Medellín durante el año 2017. Resultados: fueron encuestados 158 pacientes. La mediana de la edad fue 58 (46-68) años. El tiempo aproximado de evolución entre la edad de realización del diagnóstico principal y la edad del paciente al momento de la encuesta fue de 8.7 años, un total de 117 pacientes (74.1%) eran de sexo femenino. El estado de salud general de los pacientes de endocrinología y reumatología fue de 80 puntos, siendo los factores que afectaron la calidad de vida los denominados "dolor o malestar" y "ansiedad o depresión". Además, en los pacientes con patologías infecciosas el estado de salud general fue el más bajo, 62.5, donde el factor "dolor o malestar" fue el más común. Conclusiones: se identifica mayor alteración en las variables del EQ-5D de "dolor o malestar" y "ansiedad o depresión" en la población general, así mismo, cuando se trata del sexo femenino y de las áreas de endocrinología y reumatología.

Objective: to describe the different profiles in terms of health-related quality of life found in patients with chronic diseases in a high-complexity health institution. Methodology: cross-sectional descriptive study that evaluated the health-related quality of life through the EQ-5D instrument, in patients with chronic diseases that consulted Internal Medicine and its subspecialties in the outpatient service of a highly-complexity health institution in the city of Medellin, during the year 2017. Results: 158 patients between the ages 46-68 (an average of 58-year-old) were surveyed. A total of 117 patients (74.1%) were female. The time of evolution from the age when the diagnostic was run to the actual age of the patient when surveyed was 8.7 years. The general health status of the patients from Endocrinology and Rheumatology was found to be of 80 points, being the feelings of "pain or discomfort" and "anxiety or depression" the ones that most affected the quality of life. Additionally, in patients with infectious pathologies the general health status was the lowest (62.5); the most common factor was "pain or discomfort). Conclusions: it is evident that there is greater alteration in the variables of the EQ-5D of "pain or discomfort" and "anxiety or depression" in the general population, as well as in the females and the areas of Endocrinology and Rheumatology.

Objetivo: descrever os diferentes perfis, em termos de qualidade de vida relacionada com a saúde, em pacientes com doenças crônicas numa instituição de saúde de alta complexidade. Metodologia: estudo transversal descritivo. Se avaliou a qualidade de vida relacionada com a saúde mediante o instrumento EQ-5D em pacientes com doenças crônicas que consultaram a medicina interna e suas subespecialidades, no serviço de consulta externa de uma instituição de saúde de alta complexidade da cidade de Medellín durante o ano 2017. Resultados: foram entrevistados 158 pacientes. A média de idade foi 58 (46-68) anos. O tempo aproximado de evolução entre a idade de realização do diagnóstico principal e a idade do paciente ao momento da enquete foi de 8.7 anos, um total de 117 pacientes (74.1%) eram de sexo feminino. O estado de saúde geral dos pacientes de endocrinologia e reumatologia foi de 80 pontos, sendo os fatores que afetaram a qualidade de vida os denominados "dores ou mal-estar" e "ansiedade ou depressão". Ademais, nos pacientes com patologias infecciosas o estado de saúde geral foi o mais baixo, 62.5, donde o fator "dor ou mal-estar" foi o mais comum. Conclusões: se identifica maior alteração nas variáveis de EQ-5D de "dor ou mal-estar" e "ansiedade ou depressão" na população geral, assim mesmo, quando se trata do sexo feminino e das áreas de endocrinologia e reumatologia.

Florfenicol concentrations in milk of lactating cows postreated by intramuscular or intramammary routes

Objective. To determine the florfenicol concentration in bovine milk after intramuscular or intramammary administration to establish the optimum withdrawal time, therapeutic efficacy, and its influence on milk yield. Materials and method. Twelve healthy lactating Holstein cows were selected from the University of Antioquia’s teaching dairy herd (Colombia), were randomly assigned to a control (n=6) group or florfenicol (n=6) group that received 20 mg/kg of florfenicol by intramammary and intramuscular routes, with a 15 days washout period between treatments. Results. The Tmax and Cmax for the intramuscular route were 6 hoursand 2.86 mg/L respectively. The Tmax and Cmax for the intramammary route, were estimated at 0 hour and about 20000 mg/L respectively by extrapolated from regression line. The florfenicol elimination phase in milk had an average half-life of elimination (t½) of 19.8 hours and 4.9 hours for intramuscular and intramammary administration, respectively. The therapeutic efficacy only was reached by intramammary route, when minimal inhibitory concentration (M.I.C.) of florfenicol by Stahphylococcus aureus, was used as reference value. There was no statistically significant difference in milk yield between treated and non-treated cows. Conclusions. According to these results, post-treatment milk withdrawal should be no less than 3 days for intramammary administration, and at least 7 days for intramuscular administration. The therapeutic efficacy only was reached by intramammary route. In addition, there was no statistically significant difference in milk yield between treated and nontreated cows.

Anquilosis dentaria: revisión bibliográfica / Tooth ankylosis: a review of the literature

El objetivo de esta revisión bibliográfica es hacer una reseña sobre la anquilosis, indicando las diferentes teorías existentes hasta ahora sobre su etiología, elementos tanto clínicos como radiográficos para su diagnóstico, los efectos sobre el desarrollo de la oclusión y pautas de tratamiento

Catheter related infections in Damas Hospital

The purpose of this study is to investigate the extent of catheter-related infections in our Institution. We examined retrospectively 89 medical records of patients in whom an intravascular catheter tip culture were obtained during January through December 1991. Forty-seven catheter related infections were identified in 43 patients. There were 33 multiple lumen infected catheters and 14 single lumen. Catheters for hemodialysis were infected in 38.3 of the patients. Twenty catheters were inserted into the subclavian vein. Fifty percent of the reinserted catheters were placed in the same site, of which 28.6 became infected. Staphylococcus epidermis was isolated in 28.1 of the patients, while in 50 of the patients with Staphylococcus aureus, bacteremia was identified. Staphylococci and Enterococci were more sensitive to Vancomycin than to any other antibiotic