Clinical Value of 1.5-T Non-contrast Whole-heart Magnetic Resonance Coronary Angiography in Evaluating the Severity of Coronary Stenosis / 中国医学科学院学报

Objective To evaluate the diagnostic performance of 1.5-T non-contrast free-breathing whole-heart magnetic resonance coronary angiography(MRCA)for≥50% and≥70% coronary artery stenosis in coronary artery disease(CAD).Methods Forty-one patients clinically scheduled for invasive coronary angiography(ICA)underwent 1.5-T non-contrast free-breathing whole-heart MRCA.The diagnostic performance for≥50% and≥70% stenosis was evaluated and compared using ICA as a reference standard.Results MRCA was completed in all the 41 patients with the total acquisition time of(10.1 ± 2.2)min.The sensitivity,specificity,and accuracy of MRCA for≥50% and≥70% stenosis were 100%(95%

Effects of smoking and aerobic exercise on risk factors of metabolic syndrome among male college students / 中国学校卫生

Objective@#The aim of this study was to investigate the effects of smoking and aerobic exercise on metabolic syndrome risk factors among male college students.@*Methods@#Eighty male college students were randomly selected from Global Youth Tobacco Survey and assigned to exercise smoker(ES), non-exercise smoker(NES), exercise non-smoker(ENS) and non-exercise nonsmoker (NENS) groups with sample size of 20 in each group. Subjects in NES and NENS groups maintained daily lifestyle while those in ES and ENS group performed aerobic exercise 5 times per week for 8 weeks with exercise intensity set at 50%~80% of heart rate reserve. Before and after experiment, risk factors for metabolic syndrome were assessed including systolic blood pressure (SBP), diastolic blood pressure (DBP), waist circumference (WC), fasting plasma glucose (FPG), triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C).@*Results@#After experiment, compared with ENS and NENS group, WC, SBP, DBP, FPG and TG increased while HDL-C decreased (P<0.05) in ES and NES groups. Compared with pre-experiment, SBP and DBP significantly decreased in ENS group(P<0.05), increased in NES group (P<0.05) while no statistically significant in ES and NENS group(P>0.05); WC was significantly reduced in both ES and ENS groups(P<0.05), increased in NES group (P<0.05) while no statistically significant in NENS group (P>0.05) after experiment. Compared with NES and NENS groups, △WC in ES and ENS group decreased (P<0.05); compared with other groups, △SBP and △DBP increased in NES groups while decreased(P<0.05) in ENS group.@*Conclusion@#Smoking is associated with higher level of metabolic syndrome risk factors, while aerobic exercise is associated with lowering blood pressure and WC level in male college students.

Effect of circuit training on body composition, physical fitness, and metabolic syndrome risk factors in obese female college students / 中国学校卫生

Objective@#To investigate the effect of a 12-week circuit training program on health-related physical fitness and metabolic syndrome risk factors in obese female college students,and to provide reference for targeted interventions.@*Methods@#Sixty subjects with body mass index (BMI) over 28 kg/m2 were randomly allocated to control group ( n =30) or exercise group( n =30). Participants of control group maintained daily lifestyle while those of exercise group performed circuit training program 3 times per week for 12 weeks. Parameter of body composition (including back strength, sit-up, sit-and-reach, and 1 600 m running time), health-related physical fitness (including body height, body weight, BMI), percentage of body fat (PBF) and lean body mass (LBM) and metabolic syndrome risk factors [including waist circumference(WC), fasting blood glucose(FBG), triglyceride(TG), total cholesterol(TC), highdensity lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C)] were tested before and after the experiment.@*Results@#After intervention, body weight, BMI, PBF decreased, back strength, sit-up, sit-and-reach, and 1 600 m running time performance increased( t =2.14, 2.21, 2.48, -7.21, -7.69, -7.01, 4.83, P <0.05), WC, TG, TC reduced in exercise group compared with pre-test( t =2.89，4.54，2.71， P <0.05), whereas all parameters in control group showed no significantly different( P >0.05).@*Conclusion@#Regular circuit training improved body composition, enhanced physical fitness and may contribute to prevent metabolic diseases.

Study on clinical intervention of jiawei shengdan louxie sini fang on coronary heart disease with depression / 中国中药杂志

<p><b>OBJECTIVE</b>To study the differentiation of symptoms and signs of major syndrome factors of traditional Chinese medicine and the efficacy of Jiawei Shengdan Louxie Sini Fang combined with methods for nourishing qi and yin, promoting blood circulation, nourishing heart and kidney, soothing and nourishing liver and reducing phlegm.</p><p><b>METHOD</b>In the randomized controlled clinical trial, patients of coronary heart disease with stable angina and depression are selected and divided into the traditional Chinese medicine intervention group and the western medicine control group. Maintaining the basic treatment with western medicines for coronary heart disease, the Chinese traditional medicine group was administered with Jiawei Shengdan Louxie Sini Fang, while the western medicine control group fluoxetine.</p><p><b>RESULT</b>Compared with the control group, the traditional Chinese medicine group was better in angina curative effect, syndrome curative effect and HAMA rating scale. In the comparison for sign and symptom score, the test group was better than the control group in short of breath, lack of power, self-sweat, night sweats, insomnia, frequent micturition in night, constipation, abdominal distension, frequent deep sigh, pharynx obstruction and dark color of lips.</p><p><b>CONCLUSION</b>Intervention with traditional Chinese medicine can ameliorate angina and other symptoms of whole body. It can also improve anxiety scores of patients in order to reduce the impact of depression and anxiety on coronary heart disease.</p>

Study on the dietary pattern assessed with semi-quantitative food frequency questionnaire among rural Tibetan women with children younger than 2 years in Lhasa city / 中华流行病学杂志

Objective To explore the dietary pattern of rural Tibetan women with children under 2 years of age.Methods A cross-sectional survey on dietary pattern together with a semiquantitative food frequency questionnaire was conducted among Tibetan women in rural Lhasa in 2008.Results 386 women were investigated with the average age as 28.5 years old and average schooling-years as 4.6.For each member in the woman's family,daily intake of vegetable oil was 25.9 g on average.Daily intake of butter,sugar and salt were 27.8 g,12.9 g and 14.8 g respectively,which were higher than figures from national nutrition and health survey (P＜0.01).Among 91 kinds of food under investigation,only 22 kinds with the frequencies of consumption more than 1 time per day.Three main factors were derived by factor analysis.The first factor represented vegetable pattern characterized with vegetables,grains,fruits and a few animal foods.It was a dominant pattern for the subjects,which explained nearly 10% variance.The second one was Tibetan style pattern in which Tibetan foods and a few vegetables were consumed.The last one called meats and milk products pattern also reflected the Tibetan dietary style.Daily intake of energy for women was 2097.02 kcal which met 91.2% of Chinese recommended nutrients intake (RNI).Daily intake of protein and fat reached 82% of RNI and vitamin A but only 34.7% on RNI.Daily intake of calcium,iron and zinc reached 64.6%,174.1% and 150.7% of RNI,receptively.Grains provided 65% of energy but only 7.4% of the energy and 15.5% of protein were from animal foods."Tsampa" provided 57.6% of iron.Conclusion Vegetable pattern had been the dominant dietary pattern among Tibetan women in rural Lhasa.Intake of energy,protein and some micronutrients were not sufficient.

Dietary treatment and success rate of control in hypercholesterolemia patients treated with lipid lowering drugs: a multi-center study of current status on clinical control of hypercholesterolemia in China / 中华心血管病杂志

<p><b>OBJECTIVE</b>To assess the current status in dietary treatment of hypercholesterolemia and its effects on control of this disease in China.</p><p><b>METHODS</b>Twenty five Tertiary-A hospitals from 12 provinces in China were selected, in which 2136 patients were recruited who had had hypercholesterolemia and had been receiving lipid lowering treatment for at least 2 months. Serum lipids level was determined for each patient at the time of enrollment, and using a simplified food frequency method carried out dietary intake survey. Patients who take meat of less than 75 g per day and eggs of less than 5 per week, and fried foods of less than 5 times per week, and butter cakes and pastry of less than 5 times per week were considered as having their diet controlled.</p><p><b>RESULTS</b>Among 1746 responded patients, 68.3% reported having controlled diet. Among those reported "controlled", 75% had a diet meeting the requirements suggested by the Chinese Recommendations on Prevention and Treatment of Hypercholesterolemia (CRPTH). The percentage of patients having their serum total cholesterol under control in diet controlled group, according to the CRPTH, was significantly higher than that in diet uncontrolled group (28.8% vs 13.6%, P < 0.01). After adjustment for drug treatment and other covariates, the diet controlled group showed a significantly higher rate in control of hypercholesterolemia than the diet uncontrolled group (OR = 2.7, 95% CI: 1.4 approximately 5.2).</p><p><b>CONCLUSION</b>Diet control significantly improves the status in control of hypercholesterolemia and thus should be reinforced in routine clinical practice.</p>