1.
Basic & Clinical Medicine
;
(12): 237-240, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-693877
RESUMEN
Colon cancer associated transcript 1 (CCAT1) is a kind of long non-coding RNA (IncRNA) found re-cently, which is aberrant overexpression in colorectal cancer, and it can promote cancer cell proliferation, invasion and metastasis. CCAT1 involves in the regulation of multiple pathophysiological processes, especially the formation and progression of gastrointestinal cancer, through the interaction with microRNA (miRNA) or protein by regulation mechanism like endogenous competition, and it is expected to serve as a valuable biomarker and therapeutic target.