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Objective To study and evaluate the therapeutic safety and effect of frequency-doubled-double-pulse laser(FREDDY)lithotripsy for treating upper urinary calculi combined with acute renal failure.Methods The clinical data of 32 cases treated by frequency-doubled-double-pulse laser(FREDDY)lithotripsy were retrospectively analyzed.Results After the operation the serum BUN and Cr levels in the patients got close or returned to normal and the free rate of the stones was up to 90.6%(29/32).Conclusions The ureteroscopic frequency-doubled-double-pulse laser(FREDDY)lithotripsy has the advantage of safety,high efficiency and less trauma for treating the upper urinary tract obstruction combined with acute renal failure.It can also deal with the bilateral ureteral stones at one time.It can be the first choice when the condition is proper.
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OBJECTIVE:To establish a method for the determination of the dissolution of perospirone hydrochloride tablets(PHT).METHODS:The dissolution of PHT was determined in accordance with Chinese Pharmacopeia(2005 Edition) using water as solvent with the rotation speed at 50 r?min~(-1).The sample was taken at 30 minutes with its absorbability detected at a wavelength of 316 nm determinated by UV.Then the dissolution was calculated.RESULTS:The linear range of perospirone hydrochloride was 2～20?g?mL~(-1)(r=0.999 9)with an average recovery at 99.76%(RSD = 0.27%).The dissolutions of 3 batches of samples were all above 80%.CONCLUSION:The method was proved to be simple and reliable, and it can be used to determine the dissolution of PHT.