1.
Journal of International Oncology
;
(12): 388-391, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-400486
RESUMEN
γδT lymphocytes,a numerically small subset of T lymphocytes,have been shown to directly recognize protein antigens without restriction by polymorphic MHC class I or class Ⅱ molecules and their asso-ciated peptide ligands,secrete cytokines,kill tumor cells and display cytolytie activity against various tumors.In osteosarconla patients,γδT lymphocytes can recognize antigens expressed on the surface of osteosarcoma cells,lyse and kill tumor cells.Combined with converntional chemotherapy and surgery,the new γδT lympho-cytes-based cell immunotherapy of osteosarcoma can increase the survival rate greatly.