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Objective@#To translate the Children′s International Mucositis Evaluation Scale (ChIMES) into Chinese and evaluate its psychometric charateristics in pediatric patients with acute leukemia.@*Methods@#After translation and cognitive debriefing interviews, convenience sampling was used to recruit 105 pediatric patients with acute leukemia in a Shanghai AAA pediatric hospital.@*Results@#The known-group validity was great, and criterion validity was 0.947. Through EFA, the Chinese version of ChIMES included two dimensions which accounted for 75.270% of the accumulated variance, and each item had high factor loading quantity (>0.5). Cronbach alpha was 0.826 and the split-half reliability was 0.590. Relevance between each item and total score was good, with Pearson correlation coefficient 0.424-0.900.@*Conclusion@#The Chinese version of ChIMES has been proved valid and reliable and can be practically and feasibly used in the future.
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Objective:To translate the Children ′s International Mucositis Evaluation Scale (ChIMES) into Chinese and evaluate its psychometric charateristics in pediatric patients with acute leukemia. Methods:After translation and cognitive debriefing interviews, convenience sampling was used to recruit 105 pediatric patients with acute leukemia in a Shanghai AAA pediatric hospital.Results:The known-group validity was great, and criterion validity was 0.947. Through EFA, the Chinese version of ChIMES included two dimensions which accounted for 75.270% of the accumulated variance, and each item had high factor loading quantity (>0.5). Cronbach alpha was 0.826 and the split-half reliability was 0.590. Relevance between each item and total score was good, with Pearson correlation coefficient 0.424-0.900.Conclusion:The Chinese version of ChIMES has been proved valid and reliable and can be practically and feasibly used in the future.
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Objective To explore the related factors of severe infectious diarrhea in hospitalized pediatric patients with leukemia, and to suggest preventive nursing countermeasures. Methods Totally 81 pediatric patients, which were diagnosed with infectious diarrhea in hospitalized pediatric patients with leukemia in Shanghai Children′s Medical Center from July 2016 to December 2017,were collected and analyzed. Univariate analysis and multivariate Logistic regression analysis was carried out on the related factors affecting severe infectious diarrhea. Results There were 36 cases (44.4%) of severe infectious diarrhea occurred in 81 patients with infectious diarrhea. Multivariate Logistic regression analysis showed that the history of diarrhea ( OR=3.887) and the long duration of diarrhea with neutropenia ( OR=1.243) were risk factors for severe infectious diarrhea in hospitalized children with leukemia (P<0.05). And the results also showed that the bigger age ( OR=0.799) and the newly diagnosed leukemia ( OR=0.236) were the protective factors for severe infectious diarrhea in in hospitalized children with leukemia (P<0.05). Conclusion Prevention and treatment of diarrhea should be emphasized in pediatric patients with leukemia since newly diagnosis, and bone marrow depression should be actively ameliorated. Among those patients, smaller age and patients with repeated chemotherapy were at high risk for severe infectious diarrhea, which should be paid more attention.