Influence of different levels of skin pricking test on the short-term efficacy of subcutaneous immunotherapy in allergic rhinitis / 临床耳鼻咽喉头颈外科杂志

To explore the effect of different levels of skin pricking test on short-term efficacy of subcutaneous immunotherapy with allergic rhinitis.Thirty-one AR patients were included in our study.All the patients had received subcutaneous immunotherapy for 1 year.According to the levels of SPT the patients were divided into 3 groups(grade 2,10 persons;grade 3,10 persons and grade 4,11 persons).Of all the patients,the nasal symptoms visual analogue scale(VAS)score,medication score and rhinoconjunctivitis quality of life questionnaire(RQLQ)were investigated both before and after receiving 1 year subcutaneous immunotherapy.The total effective rate of VAS score,RQLQ score and medication score was 61.30%,58.06% and 64.52% respectively,but there was no statistical difference among the 3 groups after 1 year subcutaneous immunotherapy(P=0.573,0.136,0.699,>0.05).This study confirms the short efficacy of subcutaneous immunotherapy in AR patients with different levels of SPT.But the level of SPT was not an objective index for shortterm efficacy of subcutaneous immunotherapy of AR.

Anatomy, classification of intersinus septal cell and its clinical significance in frontal sinus endoscopic surgery in Chinese subjects / 中华医学杂志(英文版)

<p><b>BACKGROUND</b>Intersinus septal cell (ISSC) is not a very uncommon frontal recess cell. But it is poorly described in literature. The clinical significance of this anatomic variant still remains unclear. The purpose of this study was to clarify the anatomy, classification of ISSC and its clinical significance in Chinese subjects.</p><p><b>METHODS</b>We prospectively identified ISSC in 200 consecutive subjects who had undergone computed tomography (CT) scans: 120 without frontal sinusitis (group 1) and 80 with frontal sinusitis (group 2). The ISSC was classified into two types: Type I ISSC communicated with frontal sinuses, type II ISSC communicated with frontal recess. The patients of frontal sinusitis had undergone functional endoscopic sinus surgery with the assistance of the classification of ISSC. Statistical analysis was performed to correlate the ISSC and its type to the presence of frontal sinusitis.</p><p><b>RESULTS</b>The ISSC was obvious when reviewing the coronal and axial CT scans. Of the 200 CT scans reviewed, ISSC were present in 90 (45%). Of the 120 scans in group 1, ISSC were present in 49 (41%), among which type I ISSC was in 22 (18%) and type II was in 27 (23%). Of the 80 scans in group 2, ISSC was present in 41 (51%), among which type I ISSC was in 16 (20%) and type II was in 25 (31%). There were no statistically significant differences about the frequency distribution of total ISSC, type I and II ISSC between group 1 and group 2.</p><p><b>CONCLUSIONS</b>The prevalence of ISSC was very high in Chinese patients. The classification of ISSC was helpful for surgeon to operate according to whether it communicated with frontal sinus or frontal recess. The type II ISSC could be relatively easily removed from frontal recess.</p>

Investigation on Indoor Air Biological Pollution of House Which Patients With Perennial Allergic Rhinitis Lived in / 环境与健康杂志

Objective To investigate the house air pollution and its influence on the patients with perennial allergic rhinitis. Methods The method of case control study was used in 2001-2002 23 patients with perennial allergic rhinitis selected as the case and 23 normal as the control house dust mites in particular D.pteronyssinusDp and D.farinaeDf fungus bacteria was detected. Results The allergic skin test of dust and acarid were both positive among the patients with perennial allergic rhinitis. The colony of fungi in the house of patients was 917?668 cfu/m3 that of bacteria was 2 679?1 723 cfu/m3 Dp was 0.72 ?0.29100 IU/ml and Df was 0.61?0.34100 IU/ml in houses-dust compared with the control no significant deferences had been seen. Conclusion The patients with perennial allergic rhinitis are susceptible to the allergens in house dust mites.