Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Añadir filtros








Intervalo de año
1.
China Journal of Chinese Materia Medica ; (24): 4099-4103, 2013.
Artículo en Chino | WPRIM | ID: wpr-287631

RESUMEN

The antitussive activity assay for the root extraction of Disporum cantoniense was carried out with coughing mice induced by ammonia liquor. The results showed that the ethanol and water extractions of D. cantoniense possess strong antitussive activity, and the high dose of the former was better than positive control, and then the constituents of the ethanol extraction were separated and purified by various modern chromatographic techniques. Their structures were identified by physico-chemical properties and spectroscopic data. As a result, eight compounds were isolated and identified as stigmast-4-en-3-one(1), (22E, 24R)-ergosta-5, 7, 22-trien-3beta-ol(2), obtucarbamate A(3), obtucarbamate B(4), neotigogenin(5), azo-2, 2'-bis[Z-(2,3-dihydroxy-4-methyl-5-methoxy) phenyl ethylene] (6),dimethyl {[carbonylbis (azanediyl)] bis( 2-methyl-5, 1-phenylene) j dicarbamate (7) , and quercetin-3-O-pB-D-glucopyranoside(8). All compounds were isolated from this plant for the first time, and the result of bioactivity-directed isolation showed that compounds 3, 4, and 6 had obvious effect on antitussive activity, and compound 6 had the same level as positive control.


Asunto(s)
Animales , Femenino , Masculino , Ratones , Antitusígenos , Química , Farmacología , Medicamentos Herbarios Chinos , Química , Farmacología , Etanol , Química , Liliaceae , Química
2.
Acta Pharmaceutica Sinica ; (12): 533-536, 2006.
Artículo en Chino | WPRIM | ID: wpr-271412

RESUMEN

<p><b>AIM</b>To study the chemical constituents of the stem of Fordia cauliflora of Yunnan province.</p><p><b>METHODS</b>The constituents were separated and purified by repeated silica column chromatography. The structures were elucidated by physical-chemical properties and spectroscopic data.</p><p><b>RESULTS</b>Six compounds were isolated from the ethanol extract of the stem of Fordia cauliflora. They were identified as: 6-hydroxy-3-methoxy-6",6"-dimethylchromeno-(2", 3" : 7, 8)-flavone (1), 3-methoxy-6-(3-methyl-but-2-enyloxy)-6", 6"-dimethylchromeno-( 2", 3" : 7, 8)-flavone (2), 3, 6-dimethoxy-6", 6"-dimethylchromeno-( 2", 3" : 7, 8)-flavone (3), 7-hydroxy-4'-methoxyisoflavone (4), 7, 4'-dihydroxyisoflavone (5) and karanjin (6).</p><p><b>CONCLUSION</b>Compounds 1 and 2 are new compounds. Compounds 3 -5 were isolated from the plant for the first time.</p>


Asunto(s)
Fabaceae , Química , Flavonas , Química , Estructura Molecular , Tallos de la Planta , Química , Plantas Medicinales , Química
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA