Application Status and Prospect of Rehabilitation Assessment Technology / 中国医疗器械杂志

Rehabilitation assessment is the basis and important part of rehabilitation diagnosis and treatment. At present, clinical evaluation is usually carried out by observation method and scale method. At the same time, researchers monitor patients' physical condition data through sensor system and other equipment as a supplement. The purpose of this study is to review the application and development of objective rehabilitation assessment technology in clinical practice, and to discuss its limitations and strategies to provide reference for related research.

Exploration on the emergency support mode of hospital medical supplies against COVID-19 / 中华医院管理杂志

Since the outbreak of COVID-19, the hospital is faced with such challenges as sustained input in patient screening, referral and rescue, supportive medical supplies including the management of personal protective supplies and the maintenance of medical equipment. In the face of increasing workload, the medical materials support team of the hospital took the following measures in the principles of " discovering new sources of supplies and minimizing consumption" . These measures taken include proactive supply procurement strategy, prioritizing allocations based on risk exposure, uniform distribution of supplies based on inventory and usage, and traceable management for donated supplies; optimal and central deployment of equipments, emergency installation, pre-maintenance and emergency repairs for equipments; efficient and safe sterilization of reusable materials and equipments using sterilizers; enhanced personnel training and management to keep updating the medical supplies capacity of the team. All these efforts have contributed significantly to the orderly work of epidemic control.

Research on electrocardiogram classification using deep residual network with pyramid convolution structure / 生物医学工程学杂志

Recently, deep neural networks (DNNs) have been widely used in the field of electrocardiogram (ECG) signal classification, but the previous models have limited ability to extract features from raw ECG data. In this paper, a deep residual network model based on pyramidal convolutional layers (PC-DRN) was proposed to implement ECG signal classification. The pyramidal convolutional (PC) layer could simultaneously extract multi-scale features from the original ECG data. And then, a deep residual network was designed to train the classification model for arrhythmia detection. The public dataset provided by the physionet computing in cardiology challenge 2017(CinC2017) was used to validate the classification experiment of 4 types of ECG data. In this paper, the harmonic mean of classification accuracy and recall was selected as the evaluation indexes. The experimental results showed that the average sequence level ( ) of PC-DRN was improved from 0.857 to 0.920, and the average set level ( ) was improved from 0.876 to 0.925. Therefore, the PC-DRN model proposed in this paper provided a promising way for the feature extraction and classification of ECG signals, and provided an effective tool for arrhythmia classification.

Study on Material Basis and Action Mechanism of Chinese Formula Kai-Xin-San on Anti-depression via Regulation of Neurotrophic Factors / 世界科学技术-中医药现代化

Objective: To observe the material basis and mechanism of action of Kai-Xin-San (KXS) in regulating antidepression of neurotrophic factors. Methods: KXS eluted by ethanol on macroporous resin was prepared. The antidepressive effect of different components was compared by tailing suspension test and forced swimming test of mice. The levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) in hippocampus were determined by ELISA. The rat astrocyte glioma C6 cell line and the rat adrenal pheochromocytoma PC12 cell line were used to evaluate the effects of different ethanol elution sites on the expression of NGF and BDNF and the differentiation of PC12 cells.Results: All of the ethanol elution components from KXS exerted anti-depressive effects by shorting the immobile time of tailing suspension and forced swimming of mice and 70％ ethanol elution components exerted best efficacy. This site also could increase expressions of NGF and BDNF on C6 glioma cell line. The 10％ ethanol elution site had the strongest ability to promote PC12 cell differentiation. Ginsenosides were the main effectuve ingredients for promoting the expression of neurotrophic factors. Conclusion: Regulation of neurotrophic factors might be the prominent action mechanism of KXS exerting anti-depressive effects.

Detections of the Focal Regions Temperature for High Intensity Focused Ultrasound / 中国医疗器械杂志

As a tumor thermal ablation technology in cancer therapy, HIFU (High Intensity Focused Ultrasound) has been developed rapidly in recent years. With the technology becoming more and more mature, it's clinical application is becoming more and more widely. In HIFU therapy, the high-intensity ultrasound energy is focused in the target tumor tissue, generating heat within very short time, causing coagulation necrosis, so that the effect of the treatment is achieved. To ensure safe and therapeutic efficacy, HIFU therapy needs to be properly monitored by medical imaging, and temperature in the target has to be precisely measured, this article is based on the current domestic and foreign detection methods of the focal region temperature.

Application value of low dose CT scanning in lung puncture biopsy / 中国基层医药

Objective To observe the application of low dose CT scanning in lung puncture biopsy,and to discuss the feasibility and limitations.Methods 100 cases of CT guided percutaneous lung biopsy,used SPSS soft-ware to generate random numbers,odd number into the routine dose group,even number into low doses study group. The routine dose group of 50 patients underwent routine dose CT scanning(200mA,reconstruction thickness 2.0mm, pitch 16mm/rot)and puncture,and the low doses study group were given low dose CT scanning in 50 patients (10mA,reconstruction thickness 2.0mm,pitch 23mm/rot)and puncture.Two groups after routine disinfection punc-ture,were taken tissue samples for pathological examination.The two groups of CT scanning dose and image quality, the success rate of puncture and complications were compared.Results The success rate of puncture in conventional dose scan group was 90.00%;CT dose index weighted index CTDIw was (23.64 ±5.91)mGy;the average dose length product DLP was (172.31 ±43.08)mgy ×cm.The success rate of puncture of the low doses study group was 84.00%;CTDIw was (1.22 ±0.31)mgy;DLP was (8.56 ±2.14)mgy ×cm.The successful puncture rate of the two groups had no significant difference(χ2 =0.638 9,P=0.374 2);The radiation dose was statistically significant(CTDIw compare:t=2.798 3,P=0.005 4;DLP compare:t=2.684 9,P=0.007 8);The image quality can meet the need of puncture biopsy;At the same time,the two groups had no severe complications.Conclusion Low dose than routine dose CT scanning in lung biopsy success rate has no difference,but which can significantly reduce the radiation dose.

ERp in medical disposable materials management / 中华医院管理杂志

Combined with the development requirements of hospital medical disposable materials management and hospital information management,introduced a novel medical disposable materials management pattern which base on the enterprise resource planning chain supply systems.By optimizing purchasing procedure,inventory management,precision financial management,to realize the integrated management of the medical consumable materials affairs and financial affairs.

Cumulative radiation dose of multiple trauma patients during their hospitalization / 中华放射医学与防护杂志

Objective To study the cumulative radiation dose of multiple trauma patients during their hospitalization and to analyze the dose influece factors.Methods The DLP for CT and DR were retrospectively collected from the patients during June,2009 and April,2011 at a university affiliated hospital.The cumulative radiation doses were calculated by summing typical effective doses of the anatomic regions scanned.Results The cumulative radiation doses of 113 patients were collected.The maximum,minimum and the mean values of cumulative effective doses were 153.3,16.48 mSv and(52.3 ± 26.6) mSv.Conclusions Multiple trauma patients have high cumulative radiation exposure.Therefore,the management of cumulative radiation doses should be enhanced.To establish the individualized radiation exposure archives will be helpful for the clinicians and technicians to make decision wheather to image again and how to select the imaging parameters.

fMRI functional connectivity analysis of anxiety disease patients based on spatiotemporal Lyapunov exponent method / 中国医疗器械杂志

Attempting to use nonlinear spatiotemporal Lyapunov exponent to characterize fMRI brain functional connectivity of anxiety disease patients, we adopted the methods of nonlinear spatiotemporal Lyapunov exponent and linear correlation coefficients to analyses fMRI datum of 11 anxiety disease patients and 11 healthy volunteers, respectively. The results show that there are significant normalized variance exponent (NVE) differences in Inferior Frontal Gyrus (rIFG) and Medial Frontal Gyrus (MFG) between the two groups (P<0.01). And correlation coefficients shows significant differences (P<0.05). The spatial-temporal Lyapunov exponent method had higher sensitivity than the correlation coefficient method in the characterization of functional connectivity; Anxiety disease patients have abnormal functional connectivity in rIFG and MFG during our experiment.

Radiation doses in interventional radiology procedures / 中华放射医学与防护杂志

Objective To investigate the radiation doses for the patients undergoing interventional radiology and to analyze the dose - influencing factors.MethodsThe clinical data of 461 patients undergoing interventional radiology,including cerebral angiography ( CEA ),cerebral aneurysm embolism ( CAE ),superselective hepatic arterial chemoembolization ( SHAG ),coronary angiography ( COA ),percutaneous intracoronary stent implantation ( PIS1 ),cardiac radiofrequency catheter ablation ( RFCA ),and permanent cardiac pacemaker implantation(PCPI) were collected to observe the cumulative air kerma (CAK),dose area product (DAP),and fluoroscopy time,and effective dose was estimated using the conversion factors.Results The effective doses for CEA,CAE,SHAG,COA,PISI,RFCA,and PCPI were (0.33 ±0.20),(0.49 ±0.35),(6.92 ±4.19),(0.76 ±0.91),(2.35 ± 1.47),(0.50 ±0.74),and (0.67 ±0.70) Sv,respectively.In 126 of the 416 patients (26%),the effective doses were greater than 1 Sv,and the effective doses of 10 person-times were greater than 10 Sv,all of which were observed in the patients undergoing SHAG.The CAK values for CEA,CAE,SHAG,COA,PISI,RFCA,and PCPIwere (0.55 ±0.43),(1.34 ± 1.11),(0.95 ±0.57),(0.32 ±0.31),(0.91 ±0.33),(0.16 ±0.22),and (0.15 ±0.14) Gy,respectively.The CAK values were greater than 1 Gy in 59 of the 461 patients ( 12.8% ),greater than 2 Gy in 11 cases (2.4%) ,and greater than 3 Gy in 1 CEA cases and 1 CEA case,respectively.Conclusions There is a wide variation range in radiation dose for different procedures.As most interventional radiology procedure can result in clinically significant radiation dose to the patient,stricter dose control should be carried out.

The research of optimizing exposure factors in digital chest radiography / 中华放射学杂志

Objective To explore the optimum exposure factors in digital chest radiography.Methods Chest phantom was exposed under auto exposure control model with 73, 90, 125kV and S200,400,800 plus or minor 4 micro-adjust for each sensitivity grade. Meanwhile dose area product (DAP) was recorded and the value of IQFinv was analyzed automatically by Artinis CDRAD Analyzer 1.1. Ten volunteers were exposed with 73 kV, S800 - 2; 90 kV, S800 + 2 and 125 kV, S400 + 2. Two radiologists evaluated and scored image quality. Statistical analysis was performed using one way ANOVA test by SPSS 12. 0. Results ( 1 ) The quality scores of volunteers' images obtained with three combinations of exposure factors were 2. 7 ± 0. 5 for 73 kV group, 2. 9 ± 0. 3 for 90 kV group and 2. 8 ± 0. 4 for 125 kV group. The difference among them was not statistically significant ( F = 0. 587, P ＞ 0. 05 ). Whereas the DAP values were (29. 1 ± 7.9) mGy · cm2 for 73 kV group, ( 30. 5 ± 4. 5 ) mGy ·cm2 for 90 kV group and (40. 4 ±7.6) mGy · cm2 for 125 kV group, with statistically significant difference among them ( F = 9. 803, P ＜0. 01 ). (2) In all three kV conditions, DAP value of phantom declined when sensitivity increased. There was a difference of DAP value by 11％ between two successive sensitivity grades. Under the condition of same sensitivity, DAP value changed with kV in the following order: 73 kV ＞90 kV ＞ 125 kV. (3) The value of IQFinv decreased when sensitivity increased. Under the condition of same sensitivity, IQFinv changed with kV as follow: 73 kV ＞90 kV ＞ 125 kV. Conclusion The combination of exposure factors of 90 kV and S800 + 2-S800 +4 is optimum for digital chest radiography.

Reproducibility and influencing factors of 31p MR spectroscopy in rabbit liver with two-dimensional chemical shift imaging / 中华放射学杂志

Objective To investigate the reproducibility and influencing factors of relative quantification of phosphorus metabolites with two-dimensional chemical shift imaging (2D CSI) in rabbit liver. Methods Using 2D CSI MRS, 500 ml phosphate (NaH2PO4) solution phantom with 0. 05 mol/E concentration and one healthy rabbit were scanned 30 times respectively in one day and rescanned 30 times in the next day, and the stability of MR scanner and reproducibility of within-run and between-days in the same individual were analyzed. Each of thirty rabbits was scanned and rescanned one time respectively in different days, and the reproducibility of between-days in one group was analyzed. The data were statistically analyzed with t tests. Results (1) Phosphate solution phantom had a good reproducibility of within-run with the coefficient variation (CV) of 4. 92% and 5. 12% respectively in different two days. No significant change of phosphorus metabolites was detected in between-days, which was 16. 68 ± 0. 82 and 16. 56 ± 0. 85 respectively(t = 0. 665, P > 0. 05 ). (2) The CV of metabolites in one healthy rabbit ranged from 8. 04% to 34. 13%. Among the metabolites, β-ATP had the best reproducibility with the CV less than 10%. PME was 0. 88 ± 0. 28 and 0. 88 ± 0. 30, PDE was 4. 35 ± 0. 66 and 4. 35 ± 0, 66, Pi was 0. 95 ± 0.30 and 0.97±0.28, α-ATP was 5.58±0.60 and 5.61±0.61, β-ATP was 2.70±0.22 and 2.71± 0. 22, γ-ATP was 2. 20±0. 63 and 2. 18±0.44 respectively, no significant changes of metabolites were detected in between-days( P >0. 05 ). (3) The CV of metabolites in 30 healthy rabbits ranged from 8.48% to 36. 21%. Among the metabelites, β-ATP had the best reproducibility with CV less than 10%. PME was 0. 84 ± 0. 30 and 0. 79 ± 0. 28, PDE was 4. 29 ± 0.72 and 3.94 ± 0. 84, Pi was 0. 91 ± 0. 28 and 0. 92 ± 0. 31, α-ATP was 5.65±0. 66 and 5. 36±0. 60, β-ATP was 2. 71±0. 23 and 2. 66±0. 25, γ-ATP was 2. 07±0. 29 and 1.99±0. 37 respectively, no significant changes of metabolites were detected in between-days (P > 0. 05). Conclusions The relative quantification of hepatic β-ATP may be most reliable among the phosphorus metabolites for rabbit liver because of its good reproducibility and small CV. The quantification of phosphorus metabolites by 31p MRS with 2D CSI in rabbit liver is affected by many factors.

The study on relationship between energy metabolic changes tested by phosphoras-31 magnetic resonance spectroscopy and the severity of acute hepatic injury / 中华消化杂志

Objective To study the relationship between energy metabolic changes tested by phosphorus-31 magnetic resonance(MR)spectroscopy(31P MRS)and the liver damage score(LDS)in rabbit models and investigate the diagnostic value of 31P MRS in acute hepatic injury.Methods A total of 30 rabbits were received different radiation dose(ranging from 5 Gy to 20 Gy)to establish acute hepatic injury models.31P MRS was than carried out 24 hrs after radiation.The rabbits were divided into mild(LDS≤3 U),moderate(LDS 3-6 U)and severe(LDS＞6 U)hepatie injury groups.Ten healthy rabbits were served as controls.MR examination was performed on a 1.5 T imager using a 1H/31P surface coil by the 2D chemical shift imaging technique.The relative quantification of phosphomonoesters(PME),phosphodiesters (PDE), inorganic phosphate (Pi) and adenosine severe hepatic injury groups were 1.83±0.33,1.55±0.24,1.27±0.07 and 0.98±0.18,respectively,with significant differences(P＜0.05).The ATP level was progressively decreased with the increase of severity Of hepatic injury.The relative quantification of PME and Pi were decreased in severe hepatic injury group compared to control group(P＜0.05).There was no significant difference higher in moderate(1.94±0.50)and severe(1.96±0.72)hepatic injury groups compared to control group(1.43±0.31)and mild hepatic injury group(1.40+0.38)(P＜0.05).No significant difference was found in ratio of relative quantification of other phosphorus metabolites.Conclusions 31P MRS is a useful method in evaluating acute hepatic injury.The relative quantification of hepatic ATP level,which can reflect the severity of acute hepatic injury,is correlated with LDS.

Progression of Breviscapine Protecting Hepatic Ischemia-Reperfusion Injury / 中国普外基础与临床杂志

Objective To report the progression of breviscapine's protective effect to hepatic ischemia-reperfusion injury.Methods Pertinent literatures and journal articles published in recent years were reviewed,and the progression of breviscapine protecting hepatic ischemia-reperfusion injury in the experimental and clinical research were analyzed and summarized.Results The role of breviscapine is considerable extensive.It can protect hepatic ischemia-reperfusion injury by anti-oxyradical and anti-lipid peroxidation,inhibiting mitochondrial damage,intracellular calcium overload,intra-thromboxane and apoptosis,improving microcirculation,and so on.Conclusion Breviscapine plays a protective role in hepatic ischemia-reperfusion injury,and it will be of great value to application and research.

Application of Latitude Reduction Technique in CR Foot Radiography / 实用放射学杂志

Objective To evaluate the application of latitude reduction technique in CR image processing based on different tissuethickness of foot radiography.Methods The images of adult foot radiography in 50 cases were analysed retrospectively.Latitude reduction technique was used in comparison with routine CR image processing,in order to display different tissue position definition such as soft tissue in phalanges of toes,thumb nail groove,the distal of fifth phalanges,talus bone trabecula and calcaneocuboidal joint space.Results CR image processed by latitude reduction technique could showe clearly tissue and structure of foot and was super than that of routine CR image processing.(t=7.732,P

The Comparative Study of Imaging Characteristics Between "Wet"and "Dry"Laser Film / 实用放射学杂志

Objective By estimation and analysis of imaging characteristics of "dry"and "wet" laser print to appreciate the imaging quality of two different printing ways and its advantages and disadvantages respectively.Methods ①28 routine MRI and 28 routine CT images were selected,the imaging quality of MR and CT images including brightness,contrast,detail display,diagnostic performance and general impression were evaluated by 6 radiologists;②CT and MR images of skull,lumbus,knee and hand joint adjusted to the best states, then printed by "dry" and "wet" laser printer;③The sensitive characteristic curve both "dry" and "wet" printing were made with opital densimeter,SMPTE card,then an objective evaluation of stabilization was done.Results ①The imaging quality for the dry imaging possess in 56 cases,the much worse was 0.3%,the best was none,the slightly worse,medial and slightly better was 31.9%,58.9% and 8.9% respectively;②The maximum density of the dry film and the wet film was 3.34 and 3.62 respectively,the dynamic range of the latter was more wide than that of former;③The wet films exposed to temperatures from 40℃ to 100℃,did not show a noticeable alteration in optical density,but the dry film showed gray scale degradation at temperatures above 70℃.Conclusion In imaging quality,stability of film,brightness and contrast of film,"wet" laser film is better than that of "dry" laser film,but "dry"laser film has still good diagnostic function that can be used in clinical diagnosis.

Applications of CR in the Fever Outpatient Department / 实用放射学杂志

Objective To evaluate the equipment scheme and value of computed radiography (CR) in the fever outpatient department.Methods One scanner of two sets of CR system was placed to the fever outpatient department for obtaining digital images. Those images and relative clinical data were transited to department of radiology by radiological information system (RIS). Then radiologists finished the diagnostic reports and ordered the printer in the fever outpatient department to print after a necessary post-process and analysis for obtained images.Results (1) Only one radiological technician was need to work in the fever outpatient department; (2) The images could preview in 55 seconds and received chest X-ray report in 15 ～ 30 minutes after exposure.Conclusion This project adapts to routine chest X-ray of patients in the fever outpatient department because of preventing contagion and high efficiency.