Analysis the epidemiological features of 3,258 patients with allergic rhinitis in Yichang City / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To investigate the epidemiological features in patients with allergic rhinitis (AR) in Yichang city, and put forward effective prevention and control measures.@*METHOD@#Collecting the data of allergic rhinitis in city proper from 2010 to 2013, input the data into the database and used statistical analysis.@*RESULT@#In recent years, the AR patients in this area increased year by year. The spring and the winter were the peak season of onset. The patients was constituted by young men. There was statistically significant difference between the age, the area,and the gender (P < 0.01). The history of allergy and the diseases related to the gender composition had statistical significance difference (P < 0.05). The allergens and the positive degree in gender, age structure had statistically significant difference (P < 0.01).@*CONCLUSION@#Need to conduct the healthy propaganda and education, optimizing the environment, change the bad habits, timely medical treatment, standard treatment.

Expression of p53 and nm23-H1 in nasopharyngeal carcinoma and their significance / 肿瘤研究与临床

Objective To sdudy the expression of p53 and nm23-H1 proteins and their clinical significance in nasopharyngeal carcinoma.Methods The expression of p53 and nm23-H1 proteins were detected by immunohistochemistry method in 40 cases with nasopharyngeal carcinoma and 22 cases with chronic inflammation of nasopharyngeal mucosa tissues.Results Positive rates of p53 and nm23-H1 in chronic nasopharyngitis group were 1.0 ％,27.2 ％,and in the NPC group were 92.5 ％,55.0 ％.There were 9 cases with the positive expression of p53 in 22 cases of nasopharyngeal carcinoma tissues with the positive expression of nm23-H1 (40.9 ％).There were 17 cases with the positive expression of p53 in 18 cases with the negative expression of nm23-H1 (94.4 ％).The expression of p53 and nm23-H1 proteins in nasopharyngeal carcinoma were much higher than that in chronic inflammation of nasopharyngeal mucosa tissues.The expression of p53 protein in nasopharyngeal carcinoma with metastatic lymph node was higher than that in nasopharyngeal carcinoma without metastatic lymph node,but nm23-H1 protein lower.The expression of p53 protein was positively correlated with the metastasis,clinnical staging and pathological classification but not correlated with T classification of nasopharyngeal carcinoma.The expression of nm23-H1 protein was negative correlation with the metastasis and clinical staging of nasopharyngeal carcinoma.Conclusion p53 and nm23-H1 play important coordinated regulation roles in the carcinogenesis,development and metastasis of nasopharyngeal carcinoma and will probably become the key biological marks in the judging and evaluating prognosis of nasopharyngeal carcinoma.

Skin prick test of inhalative allergens for patients with allergic rhinitis in Yichang / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To investigate the allergens in patients with allergic rhinitis in Yichang, so that to find common allergens of Yichang and to provide statistic basis for a reasonable prevention and treatment to allergic rhinitis.@*METHOD@#1,979 patients with allergic rhinitis in Yichang were detected for allergens by skin prick test and the distribution of positive rates to inhaled allergens was compared between different genders and ages.@*RESULT@#1,545 (78.1%) of 1,979 suspected allergic rhinitis patients presented positive reaction. The positive rate in male was significantly higher than in female, and that in juvenile group was significantly higher than in adults. Among positive cases in inhalation group, the most common allergen was flour mite (80.4%), followed by house dust mite (64.9%), cockroach (13.3%) and artemisia pollen (8.2%).@*CONCLUSION@#The study shows that the flour mite and house dust mite are the most common inhaled allergens causing allergic rhinitis in Yichang. We should pay more attention to the prevention and treatment for the juvenile patients.

One case of epistaxis and alcohol withdrawal syndrome / 临床耳鼻咽喉头颈外科杂志

UNLABELLED@#The patient with long history of alcohol was admitted because of intermittent right nasal bleeding for two days,and treated by nasal packing. After 3 days,the patient exhibited auditory hallucinations and immediately showed rage, mania, sweating and fever. CT examination showed calcification in the right frontal lobe, brain atrophy and sinusitis.@*DIAGNOSIS@#epistaxis and alcohol withdrawal syndrome, deviated septum, sinusitis.

A case of neuroglia choristoma in middle ear / 临床耳鼻咽喉头颈外科杂志

UNLABELLED@#A 14-year-old young man presented with a white oval mass on the right side of external auditory canal.@*PHYSICAL EXAMINATION@#Under ear endoscope, a size of 0.6 cm x 0.8 cm x 0.6 cm, smooth and unmovable mass was on the right side of external auditory canal. In surgery, a cystic neoplasm which is connected to neoplasm of the external auditory canal by bone defect was found in aditus of drum sinus, and local bone defect in the back wall of drum sinus. Tympanic membrane and auditory ossicle chain is complete. Postoperative pathologic findings were consistent with neuroglia choristoma. The diagnosis mainly relied on the postoperative pathological findings.