RESUMEN
<p><b>OBJECTIVE</b>To evaluate the therapeutic efficacy of sorafenib in combination with microwave coagulation therapy (MCT) and trans-arterial chemoembolization (TACE) in patients with recurrent liver cancer.</p><p><b>METHODS</b>From January 2006 to January 2010, 90 patients with recurrent hepatocellular carcinoma (HCC) were treated with MCT and TACE in our hospital. The treatment group received sorafenib + MCT + TACE, and the control group received MCT + TACE.</p><p><b>RESULTS</b>RR of the treatment group was 66.7%, which of the control group was 52.0% (P > 0.05). DCR was 83.3% in the treatment group and 64.5% in the control group (P < 0.05). Through a comparison of survival curves along with the extension of time, the survival rates of the two groups were decreased, but the treatment group (group 1) had a significantly higher one than the control group (group 2), with a statistically significant difference (P < 0.05).</p><p><b>CONCLUSION</b>Sorafenib combined with MCT and TACE can improve the disease control rate and prolong the survival in patients with recurrent HCC.</p>
Asunto(s)
Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Antineoplásicos , Usos Terapéuticos , Carboplatino , Carcinoma Hepatocelular , Quimioterapia , Cirugía General , Terapéutica , Ablación por Catéter , Métodos , Quimioembolización Terapéutica , Terapia Combinada , Doxorrubicina , Fluorouracilo , Estudios de Seguimiento , Aceite Yodado , Neoplasias Hepáticas , Quimioterapia , Cirugía General , Terapéutica , Microondas , Usos Terapéuticos , Recurrencia Local de Neoplasia , Niacinamida , Usos Terapéuticos , Compuestos de Fenilurea , Usos Terapéuticos , Inhibidores de Proteínas Quinasas , Usos Terapéuticos , Inducción de Remisión , Tasa de SupervivenciaRESUMEN
<p><b>OBJECTIVE</b>To improve the therapeutic results of patients with glandular cystitis.</p><p><b>METHODS</b>One hundred and twenty-seven patients with glandular cystitis were treated according to their different etiological factors. The therapeutic methods included anti-infection, obstruction relief, bladder irrigation, transurethral resection, partial cystectomy, total cystectomy.</p><p><b>RESULTS</b>The patients who were associated stones and foreign bodies (50%) were cured spontaneously with an effective rate of 94%. The effective rate in patients with low urinary tract obstruction was 84%. Patients with simple urinary tract infection (53%) were cured spontaneously after anti-infection therapy. The effective rate, recurrence rate and malignancy rate in patients without associated diseases were 71%, 46% and 21% respectively.</p><p><b>CONCLUSIONS</b>Cystitis glandularis should be treated according to different etiological factors.</p>