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Objective To know the current situation of prevention and control of iodine deficiency disorders in Guangming District of Shenzhen through analyzing related monitoring indicators from 2010-2012.Methods According to the National Iodized Salt Monitoring Program,in Guangming District of Shenzhen,2 Street Offices were chosen,then 4 Neighborhood Committees were chosen in each Street Office randomly,15 household salt samples were selected randomly in each Neighborhood Committee; 5 primary schools were chosen in this district,and 20 urine samples were selected from 8-10 years old children in each school in 2011,one source water and one tap water sample were collected of all the water supply companies in this district in 2012.Salt iodine was determined by direct titration method; urinary iodine was determined by As3--Ce4+ catalytic spectrophotometry method; water iodine was determined by sulfate Ce catalytic spectrophotometry of drinking water standard test method.Results Salt iodine were 27.13 and 21.23 mg/kg in 2010 and 2012,respectively.The rates of qualified iodized salt in 2010 and 2012 were 93.33％ (112/120) and 90.00％ (108/120),respectively.The median concentration of urinary iodine of 8-10 years old children in 2011 was 208.19 μg/L.The median concentration of water iodine in 2012 was 31.60 μg/L.Conclusions The district isn't an iodine excess.The rates of qualified iodized salt in resent years are in line with national standards.There is no iodine deficiency in children and additional supplementation of iodine is not necessary.But relevant monitoring still needs to be improved.
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Objective To study the effect of lead exposure in different development periods (father BBLL and mother BBLL,MPBLL,UCBLL,IBLL,CBLL) on children behavior problems. Methods From 1996 to 2004,a nine-year epidemiological cohort study was conducted in a place with severe environmental lead pollution, Guichi district of Chizhou city in Anhui province, China. 210 newly-married couples with the intention to pregnancy and living around a lead and zinc smelt factory from Dec,1996 to Dec,1998 until delivery and then their offspring were chosen. 161 children were investigated through the questionnaires and Achenbach child behavior checklist(CBCL)at Nov,2001 and Aug,2004. Meanwhile, 210 couples baseline blood (father BBLL and mother BBLL), 93 mid-pregnancy blood(MPBLL), 98 umbilical cord blood (UCBLL),165 blood of infants(IBLL), 161 blood of children (CBLL) were collected to determined the levels of lead by PE-AA800 atomic absorption spectrophotometer. Results Geometric mean of mother BBLL, father BBLL, children BLL, infants BLL, UCBLL and MPBLL were (62.71?2.18)?g/L,(72.93?2.06)?g/L, (91.93?1.58)?g/L, (130.39?1.88)?g/L, (54.32?2.11)?g/L and (50.93?1.95)?g/L respectively,and the proportion of blood lead level at which were higher than 100 ?g/L were 32.38%, 38.10%, 45.34%, 43.03%, 10.20%, 9.68% respectively. In 161 infants, the incidence of abnormal behavior problems was 16.1%. The scores of delinquent and abruption in boys were significant higher than those in girls, while the scores of depression and social withdrawal in girls were higher than those in boys. The single correlative and the multiple stepwise regression analysis showed that the score of abruption was positively correlated significantly with MPBLL(?=0.162,P