RESUMEN
Objective To compare the lung volume before and after the operation for the treatment of chronic empyema with CT 3-dimensional imaging,and to evaluate its role in the assessment of pulmonary function. Methods A total of 78 patients with chronic empyema from 2000 to 2016 in our hospital were enrolled in this study.The patients were divided into two groups according to the operational styles,with 47 cases in the decortication group and 31 cases in the catheter drainage group respectively.Reformation of the chest CT data was used to determine the lung volumes and the routine pulmonary function tests(PFT)were performed before and after the operation. The lung volumes and the PFT results before and after the operation were compared between the two groups with t test. Then multiple linear regression analysis was applied to test the relationship between the lung volumes and the values of PFT after the operation. Results The mean lung volume of catheter drainage group was(1 548±467)cm3,while it was(1 418±802) cm3for the decortication group preoperatively(t=1.665,P=0.07).After the operation,the mean lung volume of decortication group was(2 677±815)cm3,while it was(2 169±185)cm3for the catheter drainage group. There was statistically significant difference for the increase of lung volume between the two groups after operation(t=2.371,P<0.05).There was no significant difference between the two groups before the operation for the values of the PFT(t=1.467 to 1.874,P>0.05). After the operation, the values of the PFT in the decortication group were higher than those in the catheter drainage group(t=1.990 to 2.799, P<0.05). The changes of postoperative lung volume were positively correlated with the values of the PFT(β=0.312 to 0.701,P<0.05). Conclusions Decortication has a better effect on the lung volume and the pulmonary function for patients suffered from chronic empyema. CT modeling (3-dimensional-imaging) is an effective method for evaluating the pulmonary function of postoperative lung according to the lung volume measurement.
RESUMEN
Forty-two male rats were fed with normal vitamin E( VE)requirement diet, i.e. 0.2mg?100gbw?-1d-1 for one week and then thirty-five rats were induced a 3rd degree burn of 20% BSA, another 7 uninjured rats served as normal contrsol. The burned rats were divided into 5 subgroups receiving VE at the dosage of 0.2, 1, 2, 5,10mg. 100gbw-1?d-1 respectively for 14 days. The re-ults showed that the serum and liver VE contents were lower and the serum LPO higher significantly in the burned rats as compared with the normal control,it wao also found that thymus was atrophic, the thymic cortex become thinner thymocytes constricted, and the splenic corpuscles decreased, the sperm and spermatocytes were markedly decreased with testis atrophy. Whet burned rats were fed VE, as the dosage increased to 2mg?100gbw-1?d-1, the serum and liver VE levels significantly raised and the serum LPO returned to control level. The histological changes of thymus, spleen and testes were nearly similar to the normal control rats.
RESUMEN
The effects of vitamin A on wound healing and thymus weight were studied in postoperative rats. Serum vitamin A level was significantly lowered in rats (group I) received vitamin A 6?g ? 100g bw-1?d-1. per os as.compared to the uninjured control received the same dose of vitamin A. The thymus in group I was significantly atrophic than the control. In rats received vitamin A 25?g?100g bw-1?d-1 (group Ⅱ), serum vitamin A level was kept normal and the thymus was unchanged. The histological change of the skin during wound healing nearly approached normal, and the tensile strength of the healed wound was markedly greater than in group Ⅰ. In rats received vitamin A 50?g?100g bw-1?d-1 (group Ⅲ), the effect on wound healing and the thymus was not better than group Ⅱ. A suitable dosage of vitamin A in wound healing was about 25?g?100g bw-1?d-1, i.e. 4 times the normal allowances of the rat.