RESUMEN
ObjectiveTo investigate the current status and high-risk factors of chromosomal aberrations in peripheral blood lymphocytes （PBL） of radiation workers in Hainan Province. MethodsA total of 200 radiological workers who underwent occupational health examination in Hainan Provincial Hospital of Traditional Chinese Medicine from January 2021 to December 2021 were selected to collect the occupational health examination data and the rate of PBL chromosomal aberrations. The influencing factors of PBL chromosomal aberrations were analyzed by logistic regression model. The predictive value of logistic regression prediction model on PBL chromosomal aberrations were determined by using the reciver operator characteristic （ROC） curve. ResultsA total of 20 000 cells （100 cells/person） were tested. The chromosomal aberration rate was 0.37% （74/20 000） and the PBL chromosomal aberration rate in the subjects was 6.00% （12/200）. Univariate analysis showed that PBL chromosomal aberrations in radiological workers were related to age， length of service， type of work and education （all P<0.05）， but not to gender （P>0.05）. The logistic regression prediction model was constructed based on the influencing factors， with χ2=9.413， df=9， P=0.852， suggesting a good model fit. The logistic regression prediction model predicted the area under the curve （AUC） for the occurrence of PBL chromosomal aberrations in radiation workers was 0.914 （95%CI： 0.866‒0.949）， with a cut-off value of 3.05， corresponding to a prediction sensitivity and specificity of 100.00% and 75.98%， respectively. ConclusionThe incidence of PBL chromosomal aberrations in radiological workers in Hainan Province was 6.00%， with age， working age and job type as high-risk factors and education level as a protective factor. The prediction model constructed by the above factors can provide a reliable basis for clinical prediction of PBL chromosomal aberrations in radiological workers.
RESUMEN
Objective To analyze the cut-off point of waist circumference (WC) for overweight and obesity in school children aged 7-14 in Haikou, and to provide a scientific basis for the formulation of prevention and treatment strategies for overweight and obesity in children. Methods Using the 2016-2019 “Student Health Record Management System in Hainan Province”, 220 primary and secondary schools in Haikou were sampled using the PPS sampling method, and the height, weight and waist circumference of children aged 7-14 were collected and analyzed. Results A total of 283 054 children aged 7-14 years old were investigated. The average WC and percentile WC values of children in each age group were lower the national average WC values, and the WC continued to increase with age. The WC of boys was higher than that of the girls in all age groups (P < 0.0001), and the WC of urban children was higher than that of rural children of the same age (P < 0.0001). The WC cut-off points were P75-P80 (56.50-71.75 cm) in boys and P80-P85 (54.50-68.50 cm) in girls for overweight. For obesity, the WC cut-off points in boys of 7-11 years old and 12-14 years old were P85 (58.5-72.50 cm) and P90 (75.50-79.50 cm), respectively, and the WC cut-off points in girls of 7 years old and 8-14 years old were P85 (56.50 cm) and P90 (59.85-71.50 cm), respectively. Conclusion The cut-off points of WC for overweight are 56.50-71.75 cm in boys and 54.50-68.50 cm in girls, respectively. The cut-off points of WC for obesity are 58.50-79.50 cm in boys and 56.50-71.50 cm in girls, respectively. Except for the cut-off points for overweight in 7-year-old boys and 9-year-old girls and the cut-off points for obesity in 8 to 10-year-old girls before puberty, the cut-off points for overweight and obesity in other age groups are consistent with the national values.