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Lotus medicinal herbs have the effects of resolving blood stasis and stopping bleeding， invigorating the spleen and benefiting the kidneys， restoring coordination between heart and kidney， and tranquilizing the fetus. Lotus root， lotus leaf， lotus seed， Lotus plumule， Shilianzi（Nelumbo nucifera Gaertn） and other lotus herbs are used to treat various female reproductive system diseases. For example， lotus leaf tip with modified Youshi Pangxing Shuangtu Decoction （伍尤氏胖型双土汤）， lotus root section with modified Youshi Shouxing Shuangteng Decoction （尤氏瘦型双藤汤） were used for polycystic ovary syndrome； Youshi Yangchao Formula （尤氏养巢方） （containing lotus seed）， Gengnian Formula （更年方） （containing lotus plumule） for ovarian reserve dysfunction； Lotus seed - Shihu （Dendrobium nobile） as the herb-pair， lotus stamen with ginseng flowers and Sanqi Flower for thin endometrium； Shilianzi（Nelumbo nucifera Gaertn）， lotus leaf tip， lotus stamen， lotus seed， lotus room， lotus root section can be used for premature abortion， and we summarized the characteristics of clinical medication， compounding experience， drug dosage and precautions of each lotus drug in different diseases.
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Objective:The decision tree Chi-square automatic interactive detection (CHAID) algorithm and binary Logistic regression analysis were used to construct the risk prediction model of premature ovarian failure (POF) in patients with uterine fibroids complicated with hypertension after surgery, and the results of the risk prediction model were compared and analyzed.Methods:Patients with uterine fibroids complicated with hypertension admitted to Taizhou Hospital of Zhejiang Province from Jan. 2019 to Sep. 2022 were retrospectively analyzed as the research objects. CHAID algorithm and Logistic regression analysis were used to establish risk prediction models, respectively. The area under the curve (AUC) of receiver operating characteristic curve (ROC) was used to compare and evaluate the prediction effects of the two models.Results:A total of 860 patients were collected, including 56 patients with premature ovarian function failure after operation, and the incidence of premature ovarian function failure was 6.51%. CHAID method and Logistic regression analysis showed that uterine myoma surgery, hypertension, smoking or passive smoking, family history of premature ovarian failure, sleep status, physical exercise and history of induced curettage were important influencing factors of premature ovarian failure. The accuracy of risk prediction of decision tree model was 88.2%, and the fitting effect of the model was good. The Logistic regression model Hosmer-Leme-show goodness of fit test showed that the model fit was good. The AUC of Logistic regression model was 0.893 (95% CI: 0.862-0.899), and the AUC of decision tree model was 0.882 (95% CI: 0.856-0.899). The predictive value of the two models was moderate, and there was no significant difference between them ( Z=0.254, P>0.05) . Conclusions:The combination of decision tree and Logistic regression model can find the influencing factors of premature ovarian function failure in patients with uterine fibroids complicated with hypertension after operation from different levels, and the relationship between the factors can be more fully understood. The establishment of a risk model for premature ovarian function failure in patients with uterine fibroids complicated with hypertension after surgery can provide a reference for postoperative intervention in patients with uterine fibroids complicated with hypertension, and more effectively help patients actively prevent and slow down the occurrence and development of POF.
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Objective:To investigate the expression of inflammatory factors, advanced oxidation protein products (AOPP), homocysteine (Hcy), vascular cell adhesion molecule 1 (VCAM-1) and the clinical significance of pregnancy outcome in patients with gestational diabetes.Methods:From January 2019 to January 2020, 103 cases of gestational diabetes in Taizhou Hospital of Zhejiang province were selected as observation group, and 87 normal pregnant women in Taizhou Hospital of Zhejiang province from January 2019 to January 2020 were selected as control group.The fasting blood glucose (FPG) and fasting insulin (FINS) were measured by automatic biochemical analyzer.The levels of tumor necrosis factor-α(TNF-α), high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), AOPP and VCAM-1 were measured by enzyme-linked immunosorbent assay (ELISA). The Hcy level was measured by circulating enzyme method.Results:The FPG [(8.34±1.25)mmol/L] and FINS [(9.75±0.89)U/L] in the observation group were higher than those in the control group [(4.89±0.67)mmol/L and (5.93±0.45)U/L] ( t=23.088, 36.297, all P<0.05). The serum levels of TNF-α [(21.63±3.25)ng/L], hs-CRP [(6.34±1.29)mg/L], IL-6 [(147.32±28.39)ng/L] in the observation group were higher than those in the control group [(8.72±1.84)ng/L, (2.17±0.73)mg/L and (87.96±12.41)ng/L] ( t=32.861, 26.744, 18.091, all P<0.05). The serum levels of AOPP [(53.21±9.89)μg/L], Hcy [(11.23±1.36)μmol/L] and VCAM-1 [(94.27±15.46)μg/L] in the observation group were higher than those in the control group [(25.48±6.18)μg/L, (8.41±1.28)μmol/L and (62.18±6.52)μg/L] ( t=22.674, 14.627, 18.047, all P<0.05). The incidence of adverse pregnancy outcome in the observation group (29.13%) was lower than that in the control group (4.60%) (χ 2=19.313, P<0.05). Conclusion:The patients with gestational diabetes have obvious inflammatory reaction, higher serum levels of AOPP, Hcy and VCAM-1, and poor pregnancy outcome.
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Objective@#To study the influence of community mental rehabilitation based on Deming Cycle(PDCA) management model on the quality of life of patients with chronic schizophrenia.@*Methods@#From January 2016 to June 2017, 100 patients with chronic schizophrenia who agreed to community management in Wuxi were randomly divided into study group(n=50) and control group(n=50). Both two groups received traditional community mental health services, meanwhile, the study group was provided with community mental rehabilitation based on PDCA model.All the patients were followed up for 1 year.The quality of life scales(SQLS), social disability screening schedule(SDSS) and family care index(APGAR) were assessed before and after one-year intervention.@*Results@#At the end of one year after intervention, the scores of total quality of life, psychosocial dimension, motive and energy dimension, symptom and side effects in the observation group were (41.27±10.54)points, (38.37±10.84)points, (35.43±7.46)points, (20.71±7.34)points, respectively, which were lower than those in the control group[(51.98±7.43)points, (48.73±8.72)points, (47.67±6.98)points, (29.79±8.64)points] and before intervention[(54.37±5.87)points, (49.78±4.73)points, (48.57±6.87)points, (33.17±10.42)points](t=5.87, 5.27, 8.47, 5.66, 7.68, 6.82, 9.16, 6.91, all P<0.05). At the end of one year after intervention, the social function score[(6.78±2.84)points] of the observation group was significantly lower than that of the control group[(8.83±2.73)points]and before intervention[(8.97±2.18)points](t=3.68, 4.33, all P<0.05), and the family social care index score[(8.75±2.04)points]was significantly higher than that of the control group[(7.04±2.36)points] and before intervention[(6.76±2.14)points](t=-3.88, -4.76, all P<0.05). There was a positive correlation between SDSS score and SQLS score(r=0.41, P<0.05). There was a negative correlation between SQLS score and SDSS score(r=-0.35, P<0.05).@*Conclusion@#The community mental rehabilitation strategy based on PDCA model can improve the social function and family social care, effectively improve the quality of life of schizophrenic patients, while positively promote the rehabilitation of patients.
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Objective To study the influence of community mental rehabilitation based on Deming Cycle (PDCA) management model on the quality of life of patients with chronic schizophrenia .Methods From January 2016 to June 2017,100 patients with chronic schizophrenia who agreed to community management in Wuxi were randomly divided into study group(n＝50) and control group(n＝50).Both two groups received traditional community mental health services ,meanwhile,the study group was provided with community mental rehabilitation based on PDCA model.All the patients were followed up for 1 year.The quality of life scales(SQLS),social disability screening schedule (SDSS) and family care index(APGAR) were assessed before and after one -year intervention.Results At the end of one year after intervention ,the scores of total quality of life ,psychosocial dimension ,motive and energy dimension , symptom and side effects in the observation group were (41.27 ±10.54) points,(38.37 ±10.84) points,(35.43 ± 7.46) points,(20.71 ±7.34) points,respectively, which were lower than those in the control group [(51.98 ± 7.43)points,(48.73 ±8.72)points,(47.67 ±6.98)points,(29.79 ±8.64)points] and before intervention [(54.37 ± 5.87)points,(49.78 ±4.73)points,(48.57 ±6.87)points,(33.17 ±10.42) points]( t＝5.87,5.27,8.47,5.66, 7.68,6.82,9.16,6.91,all P＜0.05).At the end of one year after intervention ,the social function score [(6.78 ± 2.84)points] of the observation group was significantly lower than that of the control group [(8.83 ±2.73) points] and before intervention[(8.97 ±2.18)points](t＝3.68,4.33,all P＜0.05),and the family social care index score [(8.75 ±2.04) points] was significantly higher than that of the control group [(7.04 ±2.36) points] and before intervention[(6.76 ±2.14)points] ( t＝-3.88,-4.76,all P＜0.05).There was a positive correlation between SDSS score and SQLS score (r＝0.41,P＜0.05).There was a negative correlation between SQLS score and SDSS score(r＝-0.35,P＜0.05).Conclusion The community mental rehabilitation strategy based on PDCA model can improve the social function and family social care ,effectively improve the quality of life of schizophrenic patients , while positively promote the rehabilitation of patients.
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Objective To understand the prevalence of attention deficit and hyperactivity disorder (ADHD) in children in China and provide scientific basis for early prevention and treatment of ADHD in children.Methods A systematic literature retrieval was conducted by using CNKI,Wanfang data,CBM and VIP databases for the information about the prevalence of ADHD in children in China published from 1979 to 2017.Pubmed database was used to retrieve the literatures about ADHD prevalence in children in China published from 1946 to 2017.The quality of literature was evaluated based on the cross-sectional study criteria according to STROBE statement.Stata 12.0 was used for combined prevalence and subgroup analyses,including gender,regions,publication year,diagnostic criteria,sampling methods,and so on.Egger testing and the evaluation of funnel graph were used to evaluate the publication bias of these literatures,and sensitivity analysis was done by using different models and eliminating the influence of any one of these articles on combined effect value.Results Twenty articles were included.The total sample size was 88 755,including 46 216 boys and 42 539 girls.The prevalence of ADHD in children in China was 5.6％ (95％CI:5.0％-6.3％).The prevalence was 7.7％ (95％CI:6.7％-8.8％) in boys and 3.4％ (95％CI:3.0％-3.8％) in girls,the difference was statistically significant (P＜0.05).No statistically significance difference in the ADHD prevalence was observed between different regions publication years,diagnostic criteria and sampling methods.Conclusions The prevalence of ADHD in children in China was high,and boys tended to have a higher prevalence compared with girls.Appropriate screening methods for early detection and intervention conduction of ADHD should be taken among children in China.
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Objective To understand the prevalence of attention deficit and hyperactivity disorder (ADHD) in children in China and provide scientific basis for early prevention and treatment of ADHD in children.Methods A systematic literature retrieval was conducted by using CNKI,Wanfang data,CBM and VIP databases for the information about the prevalence of ADHD in children in China published from 1979 to 2017.Pubmed database was used to retrieve the literatures about ADHD prevalence in children in China published from 1946 to 2017.The quality of literature was evaluated based on the cross-sectional study criteria according to STROBE statement.Stata 12.0 was used for combined prevalence and subgroup analyses,including gender,regions,publication year,diagnostic criteria,sampling methods,and so on.Egger testing and the evaluation of funnel graph were used to evaluate the publication bias of these literatures,and sensitivity analysis was done by using different models and eliminating the influence of any one of these articles on combined effect value.Results Twenty articles were included.The total sample size was 88 755,including 46 216 boys and 42 539 girls.The prevalence of ADHD in children in China was 5.6％ (95％CI:5.0％-6.3％).The prevalence was 7.7％ (95％CI:6.7％-8.8％) in boys and 3.4％ (95％CI:3.0％-3.8％) in girls,the difference was statistically significant (P＜0.05).No statistically significance difference in the ADHD prevalence was observed between different regions publication years,diagnostic criteria and sampling methods.Conclusions The prevalence of ADHD in children in China was high,and boys tended to have a higher prevalence compared with girls.Appropriate screening methods for early detection and intervention conduction of ADHD should be taken among children in China.
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Objective To observe the effect of medication compliance and self-efficacy of schizophrenia patients with diabetes by continuing self-management education. Methods A total of 60 patients with schizophrenia with diabetes diagnostic criteria were divided into experimental group (30 cases) and control group (30 cases) by the admission number, 2 groups received conventional drug treatment, the control group received general preaching health education pattern, were each issued a health education manual, with schizophrenia and diabetes health knowledge division, the test group on the basis of the continuation of the implementation of self-management education, followed up 12 months after discharge, compared 2 groups of patients with medication compliance and recurrence rate, with General Perceived Self-Efficacy Scale (GSES) assessment level of 2 groups of patients with self-efficacy, fasting blood glucose (FPG) was determined by automatic biochemical analyzer, 2 hours postprandial blood glucose (2 hPBG). Results Six months after discharge, 82.1%(23/28) cases were complete compliance, 14.3%(4/28) cases of partial compliance, 3.6%(1/28) cases of non-compliance, 55.2%(16/29)cases of the control group complete compliance, 27.6%(8/29) cases of partial compliance, 17.2%(5/29) cases of non-compliance, the differences between two groups were statistically significant (χ2=37.41, P<0.05). The 12 month test group of full compliance discharged 75.0%(21/28) cases, 14.3%(4/28) cases of partial compliance, 10.7%(3/28) cases of non-compliance, 31.0%(9/29) cases of the control group complete compliance, 31.0%(9/29) cases of partial compliance, 37.9%(11/29) cases of non-compliance, the test group compliance was higher than the control group (χ2=11.27, P<0.05). The score after 6 months and 12 months respectively for the test group general self-efficacy scored 35.32 ± 2.02, 34.18 ± 1.77, control group scored 24.03 ± 3.04, 22.48 ± 2.01, the differences between two groups were statistically significant (t=16.445, 23.304, P<0.01). After 6 months in test group FPG and 2 hPBG were (5.71 ± 1.05), (9.46 ± 1.37) mmol/L, control group were (7.79 ± 1.05),(12.28 ± 2.07) mmol/L, the differences between two groups were statistically significant (t=7.483, 6.023, P<0.01). 12 months after discharge in test group FPG and 2 hPBG respectively (5.89±1.13), (9.68±1.09) mmol/L, control group (9.14±1.19), (13.17±1.42) mmol/L, test group FPG and 2 hPBG were lower than the control group (t=10.550, 7.431, P<0.01). After 6 months and 12 months, the recurrence rate of experimental group were 7.1% (2/28) and 24.1% (7/29) respectively, and control group were 14.3%(4/28) and 44.8%(13/29), the recurrence rate of experimental group was lower than the control group, there was significant difference between 2 groups (χ2=4.326, 6.225, P< 0.05 or 0.01). Conclusions Self-management education can improve the medication compliance and self-efficacy, improve mental symptoms and sugar metabolism, and reduce the recurrence rate.
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A WeChat public platform was established according to the hospital library holdings and manpower re-sources, which can provide different kinds of individualized information service with rich contents. The advantages of WeChat public platform in providing information service for medical staff were analyzed and how to further popu-larize and improve such information service was elaborated.
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@#Objective To investigate the rehabilitation role of family-community-hospital rehabilitation management for communityschizophrenics. Methods 110 schizophrenic patients were divided into the control group (n=60) and the training group (n=50). The controlgroup were followed up once a month, while the training group participated in the family-community-hospital rehabilitation care. They wereassessed with Social Disability Screening Schedule (SDSS), General Well-Being Schedule (GWB), Self-Esteem Scale (SES) before and afterthe treatment, as well as the compliance and management of medcine questionnaire. Results No significant difference was found betweenthese groups with SDSS, happiness, self-esteem, compliance and management of medcine before the training(P>0.05), but were significantlyhigher in the training group(P<0.01). Conclusion Family-community-hospital rehabilitation management can significantly improvethe social function, the happiness, the self-esteem, the medication compliance and self-management of schizophrenia patients.
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Objective To detect the pain condition in patients with Parkinson's disease(PD) and explore the clinical significance.Methods From May 2007 to February 2008,pain was examined in 162 PD patients in Department of Neurology,West China Hospital,Sichuan University and in 135 healthy controls well matched for gender,age and education.Statistics analysis was employed according to gender,age,the form of morbility,early-onset PD or late-onset PD,duration and Hoehn-Yahr degree.Results The incidence of pain in PD patients(53.1%)was higher than that in the healthy controls(23.7%)(P