RESUMEN
BackgroundEpidural blockade is one of the most useful and versatile procedures in modern anaesthesiology. Bupivacaine a long acting amide local anaesthetic though widely used but associated with side effects like neuro and cardio toxicity. Ropivacaine,developed as a possiblealternative to Bupivacaine, has lower lipophilicity hence associated with a decreased potential for neuro and cardiac toxicity .
RESUMEN
BACKGROUND:For General anaesthesia, Endo-tracheal intubation is doneSent from Yahoo Mail on Androidusually due to that catecholamine released & deleterious haemodynamic response there . to prevent that alpha agonist dexmedetomidine & NMDA antagonist MgSO4 was used.AIM: to prevent stress response by both pharmacological agentsMATERIAL & METHODS:Both dexmedetomidine 1mcg/kg & MgSO4 30mg/kg 50% were given over 10 min slowly before induction. HR,SBP, DBP were measured at -. After intubationResults: bothdecrease Stress responseCONCLUSION: Dexmedetomidine decreases stress response in comparison to MgSO4 as MgSO4 causes mild tachycardia.