RESUMEN
Objective To study the chemical constituents of the leaves of Callicarpa nudiflora. Methods The chemical constituents were isolated and purified by column chromatography on silica gel, MPLC, and PHPLC. Their structures were elucidated on the basis of physicochemical properties and spectroscopic analysis. Results Five compounds were isolated from the leaves of C. nudiflora and elucidated as 6’-O-caffeoyl-ajugol (1), luteolin (2), 5,4’-dihydroxy-3,7,3’-trimethoxyflavone (3), luteolin-4’-O-(6’’-E-caffeoyl)- β-D-glucopyranoside (4), and 2α,3α,19α,23-tetrahydroxyurs-12-en-28-ursolic acid (5). Conclusion Compound 1 is a new compound named nudifloside A1.
RESUMEN
OBJECTIVE: To study the chemical constituents of Callicarpa nudiflora. METHODS: The chemical constituents were isolated and purified by column chromatography on silica gel, ODS, Sephadex LH-20 and MPLC. Their structures were elucidated by spectroscopic evidence and compared with those in literature. RESULTS: Nine compounds were isolated and identified as 6-O-caffeoyl ajugol(1), leucosceptoslde A(2), 6-O-caffeoly-β-glucose(3), nudifloside(4), luteolin-7-O-glucoside(5), quercetin 3'-O-β-D-glucoside(6), cistaneside C(7), acteoside(8), and syringalide A 3'-α-L-rhamnopyranoside (9). CONCLUSION: Compounds 1, 2, 6, 7, and 9 are isolated from this plant for the first time.