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1.
Journal of Chinese Physician ; (12): 1914-1917, 2021.
Artículo en Chino | WPRIM | ID: wpr-932013

RESUMEN

Reactive perforating collagenosis is a rare skin disease characterized by the expulsion of denatured collagen fibers through the epidermis. The specific pathogenesis of the disease is not clear, and according to the etiology it can be divided into hereditary and acquired. Hereditary is relatively rare, usually seen in infants, and acquired is usually seen in adults, often associated with other systemic diseases, such as diabetes, chronic renal failure, cirrhosis, pulmonary fibrosis, tuberculosis, pulmonary aspergillosis, thyroid disease, scabies, hepatitis, acquired immunodeficiency syndrome (AIDS), malignant tumors and so on. There is no standard treatment for the disease.

2.
Korean Journal of Dermatology ; : 332-334, 2019.
Artículo en Inglés | WPRIM | ID: wpr-759745

RESUMEN

A 40-year-old man presented with pruritic, multiple, variable-sized, erythematous umbilicated papules on the trunk and both extremities for 4 months. He was diagnosed with Hodgkin's lymphoma (stage IIA) after histopathologic examination of a neck mass that developed a month ago. A punch biopsy was performed on his right lower leg. Histological examination showed transepidermal elimination of the degenerated collagen. Masson's trichrome staining was performed to distinguish collagen fibers from the muscular tissue; using Masson's stain, the collagen appeared as a bluish color crossing from the dermis to the epidermis. The diagnosis of acquired reactive perforating collagenosis was made. The skin lesions showed much improvement after 6 cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy. Acquired perforating disorders are a group of cutaneous disorders that occur in adults with chronic kidney disease or diabetes mellitus. Cases of acquired perforating disorders associated with Hodgkin's lymphoma have been rarely reported in the English literature. To our knowledge, this is the first case of acquired reactive perforating collagenosis in a Korean patient with Hodgkin's lymphoma.


Asunto(s)
Adulto , Humanos , Biopsia , Bleomicina , Colágeno , Dacarbazina , Dermis , Diabetes Mellitus , Diagnóstico , Doxorrubicina , Quimioterapia , Epidermis , Extremidades , Enfermedad de Hodgkin , Pierna , Cuello , Insuficiencia Renal Crónica , Piel , Vinblastina
3.
Rev. argent. dermatol ; 97(3): 47-57, set. 2016. ilus, tab
Artículo en Español | LILACS | ID: biblio-843093

RESUMEN

Los desórdenes perforantes actualmente incluyen a la enfermedad de Kyrle, la elastosis perforante adquirida serpiginosa, la colagenosis perforante reactiva adquirida y la foliculitis perforante. Antes se consideraban entidades diferentes, pero debido a los hallazgos similares en la clínica e histopatología, se engloban dentro de este término unificador. Se manifiestan como pápulas y/o nódulos que presentan un tapón queratósico central. Su causa es desconocida, sin embargo, se las ha relacionado con distintas patologías sistémicas como la diabetes mellitus y la enfermedad renal crónica, entre otras. Se presentan dos casos de dermatosis perforante adquirida tipo colagenosis perforante reactiva, en un hombre de 69 años con antecedentes de diabetes mellitus tipo II y cirrosis hepática secundaria a infección por virus de hepatitis C y una paciente de 62 años con antecedente de diabetes mellitus tipo II.


Perforating disorders currently include Kyrle's disease, serpiginous perforating elastosis acquired, the acquired reactive perforating colagenosis and perforating folliculitis. Previously they were considered different entities, but due to similar findings in clinical and histopathology are now included within this umbrella term. The clinical findings are papules and / or nodules with a central keratotic plug and pruritus is the predominant symptom. It causes are still unknown; however they have been associated with various systemic diseases such as diabetes mellitus and chronic renal disease, among others. We report two cases of reactive perforating collagenosis one in a 69-year-old man with a history of type II diabetes mellitus and liver cirrhosis secondary to infection with hepatitis C and the other one in a 62-year-old woman with type II diabetes mellitus.

4.
Korean Journal of Dermatology ; : 828-829, 2016.
Artículo en Coreano | WPRIM | ID: wpr-98572

RESUMEN

No abstract available.


Asunto(s)
Doxiciclina
5.
Korean Journal of Dermatology ; : 728-730, 2016.
Artículo en Coreano | WPRIM | ID: wpr-24864

RESUMEN

Perforating disorders are a group of skin disorders that present the characteristic clinical finding of transepidermal elimination. Acquired reactive perforating collagenosis is an uncommon condition characterized by umbilicated hyperkeratotic papules, and in almost all cases, it coexists with other disease conditions, such as diabetes mellitus, renal failure, and malignancies. The pathologic mechanism of this disease remains largely unknown. Here, we describe the case of a 42-year-old man who developed acquired reactive perforating collagenosis after coronary artery bypass graft surgery.


Asunto(s)
Adulto , Humanos , Puente de Arteria Coronaria , Vasos Coronarios , Diabetes Mellitus , Insuficiencia Renal , Piel , Trasplantes
6.
Korean Journal of Dermatology ; : 788-791, 2008.
Artículo en Coreano | WPRIM | ID: wpr-94761

RESUMEN

Reactive Perforating Collagenosis (RPC) is a kind of perforating dermatosis, which shows transepidermal elimination of altered collagens. Acquired form is developed in an adult without family history, is favorably developed in scratched region due to pruritic sense. Acquired RPC has been reported to be associated with various systemic disorders, such as diabetes mellitus, liver disease, chronic renal failure, lymphoma, AIDS, hypothyroidism, hyperparathyroidism, and neurodermatitis, accompanied by itching & scratching. We report a case of acquired RPC in a patient with HCV hepatitis who was treated with interferon alpha. Skin lesions showed multiple erythematous centrally umbilicated, crusted papules of variable sizes on the extensor surfaces of both shins.


Asunto(s)
Adulto , Humanos , Colágeno , Diabetes Mellitus , Hepatitis , Hiperparatiroidismo , Hipotiroidismo , Interferón-alfa , Interferones , Fallo Renal Crónico , Hepatopatías , Linfoma , Neurodermatitis , Prurito , Piel , Enfermedades de la Piel
7.
Korean Journal of Dermatology ; : 1064-1069, 2007.
Artículo en Coreano | WPRIM | ID: wpr-67372

RESUMEN

Acquired reactive perforating collagenosis (ARPC) is difficult to treat. We herein report 3 cases of ARPC, which have been improved by narrowband UVB phototherapy. They had been treated with topical corticosteroid and oral antihistamine, which had no therapeutic effects on their conditions. They were treated with narrowband UVB phototherapy twice a week and four-week treatments resulted in relief of pruritus in three patients and eight-week treatments lead to significant reduction of skin lesions in two patients. Based on our experience, it is suggested that narrowband UVB phototherapy is a good therapeutic modality for recalcitrant skin lesions and severe pruritus of ARPC.


Asunto(s)
Humanos , Fototerapia , Prurito , Piel
8.
Korean Journal of Dermatology ; : 1230-1232, 2007.
Artículo en Coreano | WPRIM | ID: wpr-116291

RESUMEN

Reactive perforating collagenosis is one of a range of essential perforating disorders and is characterized by the transepithelial elimination of altered collagen. Two types have been recognized: the inherited, or childhood form and the acquired, or adult form. Acquired reactive perforating collagenosis is associated with systemic diseases, especially diabetes mellitus and/or renal failure. We report that a low-dose allopurinol showed dramatic effects on acquired reactive perforating collagenosis, which was associated with hypothyroidism and chronic renal failure caused by diabetic nephropathy.


Asunto(s)
Adulto , Humanos , Alopurinol , Colágeno , Diabetes Mellitus , Nefropatías Diabéticas , Hipotiroidismo , Fallo Renal Crónico , Insuficiencia Renal
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