RESUMEN
Based on the research results of the extraction, pharmacokinetics, and pharmacodynamics of Chinese materia medica (CMM), this paper thoroughly summarizes the principles and approaches of the corresponding mathematical models, and briefly makes a comparsion analysis on their strength and weakness. Referring to the associating data, the representatives were selected. Mathematical models with pros and cons can conduct the quantitatively analysis of study of CMM, and achieve the goals of precision, calculability, predicatability, and controllability. Mathematical models can effectively transform the qualitative problems in the study of CMM to the quantitative ones, unveil the objective laws between the quantities and promote the scientific development of CMM.