Studies on chemical constituents of Amsonia sinensis / 中草药

Object To study the chemical constituents of alkaloids of Amsonia sinensis Tsiang extracted with methanol. Methods Compounds were separated by exchange resin, macroporous resin and silica gel column chromatography. Their structures were elucidated by spectroscopic analysis. Results Three compounds were isolated from total alkaloids of A. sinensis extracted with methanol. They were identified as: rhazidigenine (Ⅰ), amsonic acid (Ⅱ), trans-sinapic acid methylester (Ⅲ). Conclusion Compound Ⅱ is a new one, and compound Ⅰ and Ⅲ are obtained from this plant for the first time.