Research process on pharmacological effect and substance basis of Perilla frutescens / 中草药

Perilla frutescens is one of traditional Chinese diaphoretics, and is produced in many areas of China. The chemical composition is rich in P. frutescens, including volatile oil, aliphatic acids, flavonoids, phenolic acids, coloring matter and so on. Because of the function of relieving superficial pathogenic factors to dissipate cold and promoting qi flowing to regulate the stomach, P. frutescens can be used to treat the diseases of wind-cold, stagnation of gastrosplenic qi, vomiting and poisoning by eating fish and crab. The study showed that P. frutescens exhibited the effects which related with the traditional uses of relieving cough, bacteriostasis, relieving fever, analgesia, etc., and besides, it showed a few new founded effects, such as sedative effects, antioxidative effects, effects of reducing blood pressure, and regulating glucose/lipid metabolism. This paper summarized the research progess on the chemical composition and main pharmacological activities of P. frutescens, and discussed its therapeutic material basis based on the summarise, which could provide a reference for the development of P. frutescens.

Study on the antioxidative effects of Radix notogingseng in experimental animals

Antioxydant effect of radix notogingseng fluid extract 1:2 was studied in mice. Experiment mice were divided randomly into 3 groups x 10 animals. Control group (group 1) was given orally with NaCl 0,9% + oliver oil infiction, group 2 was given orally with NaCl 0,9% + CCl4 infection, group 3 with notogingseng extract 5g/kg of mice. Results showed the antioxydant effect of notogingseng at moderate level. It increased the liver GSH content in comparing with intocicated group.

Study on the Antioxidative Effects of Suaeda heteoptera Kitag / 中国海洋药物

Antioxidative effects of Suaeda heteoptera Kitag. extracts were measured using thiobarbituric acid method.The results showed that extracts obtained with water,methanol and hexane gave significant resistance to the lipid peroxidation of linolenic acid and hexane extract showed the highest antioxidative activities.Mechanism of this antioxidative effect was studied using chemiluminescence.The results showed that extracts can effectively scavenge O -? 2 but have no effects on OH ?.This illustrated that the antioxidative effects were achieved by scavenging O -? 2 radical.