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1.
Medicina (B.Aires) ; 80(4): 397-400, ago. 2020. graf
Artículo en Español | LILACS | ID: biblio-1154836

RESUMEN

Resumen La traqueobronquitis aspergilar es una forma poco frecuente de aspergilosis invasiva reportada excepcionalmente en el paciente inmunocompetente. Su diagnóstico es difícil, y los tratamientos propuestos hasta ahora son de escasa efectividad, todo lo cual constituye un verdadero problema para el equipo de salud. Presentamos el caso de una paciente de 28 años, inmunocompetente y sin antecedentes epidemiológicos, que desarrolló traqueobronquitis necrotizante por aspergilosis invasiva y recibió tratamiento con voriconazol con instilación local por broncoscopia con buena respuesta.


Abstract Aspergillus tracheobronchitis is a rare form of invasive aspergillosis reported exceptionally in the immunocompetent patient. Its diagnosis is difficult, and the treatments proposed so far are of little effectiveness, all of which constitute a real problem for the health team. We present the case of an immunocompetent 28 yearsold woman, with no epidemiological background, who developed necrotizing tracheobronchitis due to invasive aspergillosis and received voriconazole with local instillation by bronchoscopy with a good response.


Asunto(s)
Humanos , Femenino , Adulto , Aspergilosis , Infecciones del Sistema Respiratorio , Traqueítis , Bronquitis , Broncoscopía , Antifúngicos
2.
The Korean Journal of Critical Care Medicine ; : 67-71, 2013.
Artículo en Coreano | WPRIM | ID: wpr-646454

RESUMEN

Invasive aspergillosis is a serious threat and a leading cause of death in immunocompromised patients. Aspergillus tracheobronchitis is an infrequent but severe form of invasive pulmonary aspergillos in which the fungal infection is entirely or predominantly confined to the tracheobronchial tree. We report an extraordinary case of acute airway obstruction and respiratory failure due to Aspergillus tracheobronchitis in an immunocompromised patient. Fiberoptic bronchoscopy revealed extensive obstruction of both the main and lobar bronchus with yellowish nodules strongly adhered to the bronchial wall; both histologic examination and culture of these nodules revealed Aspergillus fumigatus. Even with early detection of an intraluminal growth of Aspergillus and prompt institution of antifungal therapy, the patient died of refractory hypoxemia a few days later. This report shows that Aspergillus tracheobronchitis should be considered in immunocompromised patients with suspected lung infection even when the main radiographic finding is atelectasis.


Asunto(s)
Humanos , Obstrucción de las Vías Aéreas , Hipoxia , Aspergilosis , Aspergillus , Aspergillus fumigatus , Bronquios , Broncoscopía , Causas de Muerte , Huésped Inmunocomprometido , Pulmón , Atelectasia Pulmonar , Insuficiencia Respiratoria
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