Analysis on application value of heated humidifier of BiPAP ventilator in the treatment of type II respiratory failure / 中国医学装备

Objective: To analyze the application value of heated humidifier and water humidifier of BiPAP ventilator in the treatment of type II respiratory failure. Methods: The clinical data of 50 patients with type II respiratory failure were statistically analyzed, and these patients were divided into heated humidifier group (adopted heated humidifier, n=25) and water humidifier group (adopted water humidifier, n=25) according to the difference of humidifying device of BiPAP ventilator. The PaO2, PaCO2, pH and the effect of humidifier for upper respiratory tract with dry sensation between pre-and post treatment were analyzed by statistical method. Results: The values of PaO2and pH of heated humidifier group were significantly higher than that of water humidifier group (t=4.303, t=3.182, P<0.05), respectively. While the PaCO2of heated humidifier group was significantly lower than that of water humidifier group (t=6.965, P<0.05). In the contrast of dry sensation of upper respiratory tract, the ratio of non-dry sensation in heated humidifier group was 84.0% (21/25) and it was 32.0% (8/25) in water humidification group, and the difference between the two groups was significant (x2=12.83, P<0.05). And the ratio of general dry sensation in heated humidifier group was 16.0% (4/25) and it was 40.0% (10/25) in water humidification group, and the ratio of heated humidifier group was significantly lower than that of water humidifier group (x2=5.02, P<0.05). Besides, the ratio of worst dry sensation in heated humidifier group was 0 and it was 28.0% (7/25) in water humidifier group, and the ratio of heated humidifier group was significantly lower than that of water humidifier group (x2=7.38, P<0.05). Conclusion: In the treatment of type II respiratory failure by using BiPAP ventilator, the application value and effect of heated humidifier is higher than that of water humidifier, so it is worthy to promote and use the heated humidifier in clinical practice.

Estudio comparativo de dos modos de ventilación no invasiva para retirar la asistencia respiratoria mecánica en lactantes post-operatorios de cirugía cardiovascular / Comparative study of two modalities of non-invasive ventilation for the weaning from mechanical ventilation of post-cardiovascular surgery infants

La mejor estrategia en el post-quirúrgico de cardiopatías congénitas para promover la extubación precoz y destete de asistencia respiratoria mecánica (ARM) con ventilación no invasiva (VNI) todavía no ha sido establecida. El objetivo es comparar eficacia de la presión positiva continua en la vía aérea (CPAP) vs presión positiva con dos niveles en la vía aérea (BIPAP) en la extubación electiva de estos pacientes. Es un estudio prospectivo entre el 1 de junio de 2008 y 31 marzo de 2010. Se randomizaron los pacientes para extubación electiva: modo CPAP o BIPAP. Se registraron datos demográficos y del procedimiento quirúrgico, entre otros. El fracaso de VNI fue definido como reintubación dentro de las 72 hs posteriores a la extubación o más de un criterio de intubación. Durante el periodo de estudio 1438 pacientes fueron admitidos en UCI35. En el grupo BIPAP se randomizaron 53 pacientes, de los cuales se extubaron exitosamente 49 (92%), pero 4 se reintubaron debido a falla cardiaca. En el grupo CPAP se randomizaron 46 y fallaron en la extubación 18 (39%) debido a múltiples episodios de desaturación y apneas. De éstos, 11 requirieron reintubación endotraqueal y ARM. En 7 pacientes, se pasó a modo BIPAP y permanecieron extubados, aunque el cruzamiento no fue parte del diseño de este estudio. En el destete de ARM de los pacientes post-quirúrgicos de cardiopatías congénitas, el uso de BIPAP fue más efectivo que CPAP. En esta última modalidad se presentaron mayor número de fracasos de VNI (AU)

The best strategy for early extubation and weaning from mechanical respiration (MV) with non-invasive ventilation (NIV) in post-surgical congenital heart defect patients has not been established yet. The aim of this study was to compare the efficacy of continuous positive airway pressure CPAP) vs bi-level positive airway pressure (BIPAP) in the elective extubation of these patients. A prospective study was conducted between June 1, 2008 and March 31, 2010. Patients that were candidates for elective extubation were randomized to CPAP or BIPAP. Data on demographics and surgical procedure, among others, were recorded. Failure of NIV was defined as the need for reintubation within 72 hours after extubation or more than one criterion for intubation. Over the study period, 1438 patients were admitted to ICU 35. Fifty-three patients were randomized to BIPAP, of whom 49 (92%) were successfully extubated; however, four were reintubated due to heart failure. Forty-six patients were randomized to CPAP. Extubation failed in 18 (39%) due to multiple episodes of desaturation and apneas. Eleven of 18 required endotracheal reintubation and mechanical ventilation. Seven patients were switched to BIPAP and remained extubated, although the switch was not part of the study design. In the weaning of post-surgical congenital heart defect patients from MV, BIPAP was more effective than CPAP. In the latter modality, the incidence of NIV failure was higher (AU)

Um anjo para ELA: arquitetura baseada em visão computacional aplicada ao monitoramento on-line de parâmetros respiratórios de pacientes com Esclerose Lateral Amiotrófica (ELA) em ambiente hospitalar / An angel for ALS: architecture based on computer vision applied for on-line monitoring respiratory parameters of patients with Amyotrophic Lateral Sclerosis (ALS) in hospital environment

INTRODUÇÃO: A Esclerose Lateral Amiotrófica (ELA) é uma doença neurodegenerativa, caracterizada por uma progressiva e fatal perda de neurônios motores do córtex cerebral, tronco encefálico e medula espinhal, mas que mantém preservada a atividade intelectual e cognitiva do paciente. Pacientes acometidos por essa doença irão invariavelmente necessitar do auxílio de ventiladores mecânicos. MÉTODOS: Foi utilizado um conjunto de hardware e software para realizar o monitoramento dos parâmetros respiratórios dos pacientes em leitos hospitalares como forma de auxiliar à equipe de saúde. O monitoramento desses parâmetros deu-se por meio de uma webcam, que capturava os valores exibidos na tela do ventilador mecânico, e do emprego de técnicas de visão computacional e Optical Character Recognition (OCR). Neste sentido, o sistema foi testado sob três condições de luminosidade diferentes para verificar a eficácia do mesmo. RESULTADOS: O sistema apresentou uma média geral de acertos de 94.90%. Além disso, quando a interferência luminosa foi mínima, o sistema obteve uma média geral de acertos de 97,76%. CONCLUSÃO: A adoção de um sistema computacional baseado em visão computacional para auxílio da equipe de saúde no monitoramento hospitalar de pacientes com ELA mostrou-se satisfatória. No entanto, a pesquisa mostrou que a adoção de um sistema com maior imunidade à interferências luminosas externas tende a apresentar melhores resultados.

INTRODUCTION: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by a progressive and fatal loss of motor neurons in the cerebral cortex, brainstem and spinal cord. In spite of that, the patient's intellectual and cognitive activity remains preserved. Patients affected by this disease will invariably need the help of mechanical ventilators. METHODS: A set of hardware and software was used to perform the monitoring of respiratory parameters of patients in hospital beds as a means of assisting the healthcare team. The monitoring of these parameters was performed by a webcam that captured the values displayed on the screen of the ventilator, and the employment of computer vision techniques and Optical Character Recognition (OCR). In this sense, the system was tested under three different lighting conditions to verify its effectiveness. RESULTS:The system presented an overall average of 94.90% of correct answers. Furthermore, when the luminous interference was minimum, it achieved an overall average of success of 97.76%. CONCLUSION: The adoption of a computational system based on computer vision to aid the healthcare team in hospital monitoring of patients with ALS was satisfactory. However, the research has shown that the adoption of a system with greater immunity to external light interference tends to achieve better results.

Effect of non-invasive bi-level positive airway pressure ventilation combined with naloxone in the treatment of AECOPD complicated with pulmonary encephalopathy:a meta-analysis / 中华行为医学与脑科学杂志

Objective To review the effect of non-invasive bi-level positive airway pressure ventilation combined with naloxone in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated with pulmonary encephalopathy (PE).Methods Related published studies involving BiPAP combined with naloxone in the treatment of AECOPD complicated with PE were recruited and identified from Pubmed,ISI Web of knowledge,CBM Disc,CNKI,Wanfang Data,and randomized controlled trails(RCTs) primarily collected were screened according to inclusive criteria and exclusive criteria.Valid data were extracted after quality evaluation for meta-analysis utilizing RevMan 5.2.Results A total of 10 Chinese RCTs were enrolled,including 697 patients (353 patients in experimental group while 343 patients in control group).The results of metaanalysis indicated that BiPAP combined with naloxone improved PaO2 (WMD =4.10,95％ CI (2.83,5.38),P＜0.00001),PH value(WMD =0.04,95％ CI (0.02,0.05),P ＜ 0.00001) and clinical efficiency rate (OR =3.58,95 ％ CI ((2.22,5.76),P ＜ 0.00001),and reduced PaCO2 (WMD =-5.78,95 ％ CI (-6.87,4.69),P ＜ 0.00001),re-endotracheal intubation rate (OR =0.19,95 ％ CI (0.11,0.35),P ＜ 0.00001),but failed to decrease mortality(OR =0.38,95％ CI (0.11,1.34),P =0.13) of patients with AECOPD complicated with PE.Conclusions BiPAP combined with naloxone play a protective role in enhancing arterial blood gas indexes,improving clinical efficiency rate and limiting re-endotracheal intubation rate.However,the mortality of patients cannot be reduced.

Influence of comprehensive nursing intervention on clinical effect of patients with non-invasive mechanical ventilation with BiPAP mode / 中国实用护理杂志

ObjectiveTo investigate the treatment effects of comprehensive nursing intervention on patients with chronic obstructive pulmonary disease(COPD) treated by non-invasive mechanical ventilation with BiPAP mode.Methods96 patients with diagnosed COPD and using non-invasive mechanical ven- tilation with BiPAP mode were randomly divided into the control group(46 cases) which was treated with routine measures and the comprehensive nursing intervention group (50 cases) which adopted comprehen- sive nursing intervention according to experimental design. The frightening degree, incidence rate of com- plications and clinical treatment effect by ventilator were compared between the two groups.ResultsPa- tients compliance with treatment and clinical treatment effect by ventilator in the comprehensive nursing in- tervention group was better than that of the control group. The frightening degree and incidence rate ofcomplications were lower than those of the control group (P < 0.01 ).ConclusionsComprehensive nurs-ing intervention with non-invasive mechanical ventilation with BiPAP mode can improve the treatmentcompliance of COPD patients,reduce complications followed by non-invasive mechanical ventilation andreach the prospective treatment effect.

Ventilación mecánica prolongada con BiPAP a través de traqueostomía / Long-term noninvasive ventilation via tracheostomy

No existen reportes que describan el uso de equipos generadores de flujo con presión diferencial en 2 niveles (BiPAP) a través de traqueostomía para entregar ventilación mecánica prolongada (VMP) en niños. Este documento describe los criterios de selección, modalidad de uso y requerimientos tecnológicos como guía para implementar esta estrategia ventilatoria.

Ventilação não-invasiva no edema agudo de pulmão cardiogênico: [revisão] / Noninvasive ventilation in acute cardiogenic pulmonary edema: [review]

O uso da continuous positive airway pressure (CPAP) no tratamento do edema agudo de pulmão (EAP) cardiogênico tem sido estudado por alguns autores. Recentemente, a utilização da ventilação não-invasiva com dois níveis de pressão (BiPAP) vem sendo estudada nessa situação clínica; entretanto, os resultados são controversos. Dessa forma, foi realizado, através do MEDLINE, um levantamento dos ensaios clínicos randomizados publicados em língua inglesa que analisaram a utilização do BiPAP em pacientes com EAP cardiogênico, obtendo-se um total de 11 trabalhos. O BiPAP mostrou-se útil no manuseio do EAP, apresentando benefícios similares à CPAP. Nos pacientes hipercápnicos, o BiPAP surge como uma importante estratégia de suporte ventilatório não-invasivo. Porém, faz-se necessário um estudo com grande número de pacientes para esclarecer certas dúvidas ainda persistentes.

The use of continuous positive airway pressure (CPAP) in the treatment of acute cardiogenic pulmonary edema (CPE) has been studied by some authors. Recently, the use of bi-level positive airway pressure (BiPAP) has been studied in this clinical situation, although the results have been controversial. We searched MEDLINE in order to find randomized trials published in English that analyzed the use of BiPAP in patients with CPE. Eleven trials were found. BiPAP was useful in the management of CPE, showing similar benefits to those of CPAP. In hypercapnic patients, BiPAP appears to be an important strategy of noninvasive ventilatory support. However, large trials are necessary to clarify certain doubts that still remain.

Clinical Evaluation of BiPAP in the Treatment of Refractory Asthma / 医学研究杂志

Objective To discuss the effect and feasibility of BiPAP in refractory asthma patients. Methods A total of 15 coses of refractory bronchial asthma admitted by our hospital during Feb 2003 to May 2006 were treated by BiPAP in addition to medical therapy。 The symptoms、signs and the arterial blood gases were observed and analyzed。Results Among 15 patients,2 gave up treatment,13 patients were successfully treated with the BiPAP therapy。There were significant improvement of PaCO2、PaO2、pH and respiratory rate ,heart rate after 2h BiPAP。Conclusions Ventilation in BiPAP is an effective method for refractory asthma ,which can save the patients life and decrease the complications.

Effect of positive pressure ventilation on the radiotherapy of Hunmn Primary Lung Cancer of Stage Ⅲ / 中国实用内科杂志

Objective To investigate the effect of positive ventilation pressure on the radiotherapy of primary cancer of stage Ⅲ.Methods 19 patients diagnosed as of primary,cancer of stage Ⅲ were randomly divided into two groups:the combining therapy group and the simple radiotherapy group.The patients of combining therapy group were treated with positive pressure ventilation using BIPAP respirator and radiotherapy.The recently therapy results and the radiotherapy associated side effects were observed between these two groups.Results(1)The combination of radiotherapy and BI- PAP provides significant superiority of local effects over radiotherapy.P

23 cases of COPD patients with acute exacerbation of chronic respiratory failur disease by non-invasive treatment on BiPAP synchrony / 中国实用内科杂志

Objective To explore the treating effects of COPD(chronic obstructive pulmonary disease)patients with acute exacerbation of chronic respiratory failure by the BiPAP Synchrony(Bi-level positive airway pressure).Methods45 cases of COPD patients with acute exacerbation of chronic respiratory failure are randomly divided into the observation group(23 cases)and the control group(22 cases).For the observation group,beside routine treatment,non-invasive treatment on BiPAP Synchrony is adopted.For the control group,Nikethamide is added in the routine treatment.Compare patients' heart beat rates,breathing rates and oxygen concentrations as well as patients' own feeling in these two groups.ResultsIn the observation group,the patients' heart beat rates,breathing rates and oxygen concentrations as well as patients' own feeling are better than those in the control group(P

Sequential treatment for patients of bronchial asthma accompanied by pneumothorax / 第三军医大学学报

Objective To study the curative effect of noninvasive ventilation on the patients of acute serious bronchial asthma complicated with pneumothorax. Methods Forty patients were randomly assigned to receive BiPAP ventilation immediately after thoracic closing drainage, or nasal catheter oxygen inhalation after thoracic closing drainage. Results After 24-hour ventilation, the levels of PO_ 2, SO_ 2, PCO_ 2 and breath rate between two groups were of remarkable difference (P0.05). The level of PO_ 2, SO_ 2, PCO_ 2, and heart rate, respiratory rate of the BiPAP patients were of remarkable difference (P

Asistencia ventilatoria no invasiva domiciliaria nocturna en pediatría / Pediatric nocturnnal noninvasive ventilation assistance at home

The nocturnal noninvasive ventilation (NNIV) at home is often used in chronic respiratory failure (CRF) and obstructive sleep apnea (OSA) and, less frequently, in central hypoventilation and cystic fibrosis. We present a 6 year period (1996-2002) retrospective review of 10 children treated with noninvasive respiratory support describing indications, type of NNIV and the follow-up. Patient's age ranged from 1 to 13 years old; 6 were females and 4 males. Six had a neuromuscular disease, three a cerebral palsy and one an Arnold Chiari Syndrome Type II. Nine children presented kyphoscoliosis. NNIV was indicated in the following conditions: compensated CRF (n = 3), decompensated CRF (n = 1), acute respiratory failure with underlying neuromuscular diseases and unclear diagnosis of CRF (n = 2); OSA with pharyngeal collapse (n = 3) and central hypoventilation (n = 1). Two patients had moderate to severe pulmonary restriction and subnormal maximal airway pressures. Six patients were discharged with CPAP and four with BiPAP after being hospitalized during 3 to 90 days. In average, the follow-up lasted 2 years. Three children had training of their respiratory muscles. One patient needed a tracheostomy, the other nine improved: five without re-admissions and four reduced them. Five patients went back to school. One patient with congenital myopathy and kyphoscoliosis, surgically treated, improved her pulmonary function and the 6 minutes walking test. Two patients used NNIV irregularly and other two stopped it after one year. No deaths were reported. In our experience NNIV at home lessens admissions and promotes a better social and school re-integration. BiPAP is useful in restrictive conditions meanwhile CPAP is helpful in upper airway obstruction with OSA.

La asistencia ventilatoria no invasiva domiciliaria nocturna (AVNIDN) se indica en insuficiencia respiratoria crónica (IRC), síndrome de apnea obstructiva del sueño (SAOS) y ocasionalmente por hipoventilación central y fibrosis quística. Se hace una revisión retrospectiva de 10 pacientes sometidos a esta técnica de soporte ventilatorio no invasivo durante un periodo de 6 años (1996-2002), describiendo las indicaciones, tipo de AVNIDN y el seguimiento. Sus edades fluctuaron entre 1 a 13 años; 6 mujeres y 4 hombres. Seis pacientes tenían enfermedad neuromuscular; 3 parálisis cerebral y uno Arnold Chiari tipo II. Nueve presentaban xifoescoliosis. Las indicaciones fueron: IRC estable 3 pacientes; posterior a IRC descompensada 1; luego de insuficiencia respiratoria aguda en enfermos neuromusculares sin diagnóstico claro de IRC, 2 pacientes. SAOS secundaria a faringomalacia en 3 y por hipoventilación central uno. Dos presentaban restricción pulmonar moderada a severa y presiones máximas de vía aérea subnormales. Seis pacientes recibieron CPAP y 4 Bipap. El tiempo de hospitalización previo al alta fue de 3 a 90 días y la duración promedio del seguimiento fue 2 años. Tres recibieron entrenamiento muscular respiratorio. No hubo mortalidad; un paciente fue traqueostomizado. Nueve mejoraron, 5 no tuvieron rehospitalizaciones y 4 las disminuyeron. Cinco pacientes asisten al colegio. Un paciente con miopatía congénita y artrodesis mejoró sus pruebas funcionales respiratorias y la distancia recorrida en 6 minutos. Dos usaron irregularmente la AVNIDN y dos suspendieron tratamiento luego de un año. En nuestra experiencia, la AVNID minimizó las hospitalizaciones y promovió la reinserción social y escolar. La modalidad Bipap fue útil en patologías restrictivas y el CPAP en obstrucción de vía aérea superior/SAOS.

Nasal Mask BiPAP for the Chronic Obstructive Pulmonary Disease with Kyphoscoliosis / 대한마취과학회지

Chronic fatigue of the respiratory muscles has contributed to the decreased ventilatory capacity and reduced excercise tolerance of individuals with COPD, especially in kyphoscoliosis. Nasal mask BiPAP has been shown to be useful for the patient with nocturnal muscle fatigue and COPD. A 35-year-old man with severe kyphoscoliosis was admitted to ICU due to acute respiratory failure. He had been diagnosed of COPD and had been intubated with mechanical ventilatory support for 7 times. This time he was intubated with ventilatory support, too, in ICU and readmitted to the ICU for severe hypoxemia and hypercarbia from general ward. Thereafter he refused the intubation. Nasal mask BiPAP ventilatory support system was applied and IPAP, EPAP level being adjusted to the 12, 4 cmH2O under monitoring vital signs and arterial blood gas analysis. His condition was improved and discharged home with support of nasal mask BiPAP system after 33 day-stay in the ICU.

The Effect of Nasal BiPAP Ventilation in Acute Exacerbation of Chronic Obstructive Airway Disease / 결핵

BACKGROUND: Mechanical ventilation constitutes the last therapeutic method for acute respiratory failure when oxygen therapy and medical treatment fail to improve the respiratory status of the patient. This invasive ventilation, classically administered by endotracheal intubation or by tracheostomy, is associated with significant mortality and morbidity. Consequently, any less invasive method able to avoid the use of endotracheal ventilation would appear to be useful in high risk patient. Over recent years, the efficacy of nasal mask ventilation has been demonstrated in the treatment of chronic restrictive respiratory failure, particularly in patients with neuromuscular diseases. More recently, this method has been successfully used in the treatment of acute respiratory failure due to parenchymal disease. METHOD: We assessed the efficacy of Bilevel positive airway pressure(BiPAP) in the treatment of acute exacerbation of chronic obstructive pulmonary disease(COPD). This study prospectively evaluated the clinical effectiveness of a treatment schedule with positive pressure ventilation via nasal mask(Respironics BiPAP device) in 22 patients with acute exacerbations of COPD. Eleven patients with acute exacerbations of COPD were treated with nasal pressure support ventilation delivered via a nasal ventilatory support system plus standard treatment for 3 consecutive days. An additional 11 control patients were treated only with standard treatment. The standard treatment consisted of medical and oxygen therapy. The nasal BiPAP was delivered by a pressure support ventilator in spontaneous timed mode and at an inspiratory positive airway pressure 6-8cmH2O and an expiratory positive airway pressure 3-4cmH2O. Patients were evaluated with physical examination(respiratory rate), modified Borg scale and arterial blood gas before and after the acute therapeutic intervention. RESULTS: Pretreatment and after 3 days of treatment, mean PaO2 was 56.3mmHg and 79.1mmHg (p<0.05) in BiPAP group and 56.9mmHg and 70.2mmHg (p<0.05) in conventional treatment (CT) group and PaCO2 was 63.9mmHg and 56.9mmHg (p<0.05) in BiPAP group and 53mmHg and 52.8mmHg in CT group respectively. pH was 7.36 and 7.41 (p<0.05) in BiPAP group and 7.37 and 7.38 in CT group respectively. Pretreatment and after treatment, mean respiratory rate was 28 and 23 beats/min in BiPAP group and 25 and 20 beats/min in CT group respectively. Borg scale was 7.6 and 4.7 in BiPAP group and 6.4 and 3.8 in CT group respectively. There were significant differences between the two groups in changes of mean PaO2, PaCO2 and pH respectively. CONCLUSION: We conclude that short-term nasal pressure-support ventilation delivered via nasal BiPAP in the treatment of acute exacerbation of COPE), is an efficient mode of assisted ventilation for improving blood gas values and dyspnea sensation and may reduce the need for endotracheal intubation with mechanical ventilation.

Clinical Application of Nasal Intermittent Positive Pressure Ventilation with Bi-level Positive Airway Pressure(BiPAP) / 결핵

BACKGROUND: Noninvasive ventilation has been used extensively for the treatment of patients with neuromuscular weakness or restrictive chest wall disorders complicated by hypoventilatory respiratory failure. Recently, noninvasive positive pressure ventilation has been used in patients with alveolar hypoventilation,chronic obstructive pulmonary disease(COPD),and adult respiratory distress syndrome. Sanders and Kern reported treatment of obstructive sleep apnea with a modification of the standard nasal CPAP device to deliver seperate inspiratory positive airway pressure(IPAP) and expiratory positive airway pressure(EPAP).Bi-level positive airway pressure (BiPAP) unlike nasal CPAP, the unit delivers a different pressure during inspiration from that during expiration The device is similar to the positive pressure ventilator or pressure support ventilation. METHOD AND PURPOSE: Bi-level positive airway pressure(BiPAP) system(Respironics, USA) was applied to seven patients with acute respiratory failure and three patients on conventional mechanical ventilation. RESULTS: 1) Two of three patients after extubation were successfully achieved weaning from conventional mechanical ventilation by the use of BiPAP ventilation with nasal mask. Five of seven patients with acute respiratory failure successfully recovered without use of conventional mechanical ventilation. 2) PaO2 lhour after BiPAP ventilation in acute respiratory failure patients significantly improved more than baseline values(p<0.01)). PaCO2 lhour after BiPAP ventilation in acute respiratory failure patients did not change significantly more than baseline values. CONCLUSION: Nasal mask BiPAP ventilation can be one of the possible alternatives of conventional mechanical ventilation in acute respiratory failure and supportive method for weaning from mechanical ventilation.

The Effect of Noninvasive Ventilation(NIV) in Treating Severe Asthma Resisting Incretion / 昆明医科大学学报

Objective To study the effect of BiPAP NIV in treating severe asthma that resists incretion.Method 38 asthma patients that resist incretion were selected with 19 patients given BiPAP NIV and the other 19 patients given oxyen by nasal catheter.We study the changes of blood gas analysis and days of hospitalization.Result After 4 days' treating,two group patients' PO_2 increase obviously and their dyspnea alleviate.In BiPAP NIV group,PO_2 is higher than that of the control group(P

Development and New Technology of Sleep Non-invasive Ventilator / 医疗卫生装备

Sleep apnea syndrome(SAS) and its harm to the health are briefly introduced,the review on history and classification of sleep non-invasive ventilator is presented,and therapy mechanism of CPAP on SAS is described.Furthermore,the specifications of three popular CPAP in the market are compared and some new technologies of CPAP are discussed.

Clinical Observation and Influence Factor Analysis on Treatment of the Aged COPD with Acute Respiratory Failure by Using Harmless Bi-level Positive Airway Pressures / 重庆医科大学学报

Objective:To evaluate the clinical efficacy and analysis influence factors on treatment of the aged COPD with acute respiratory failure by using harmless bi-level positive airway pressure. Method:Twenty-five patients who were identified the aged COPD with acute respiratory failure were divided into two groups randomly:13 in treatment group in which BiPAP was used in addition of conventional treatment;12 in control group in which nasal catheter oxygen inhalation was used. The change of the arterial blood gas and the clinical performance were observed before and 2 hours、72 hours 、120hours after treatment. Result: It is confirmed that the BiPAP can raise PaO2, lower PaCO2, improve PH,HR and R(P