A randomized comparative study on the effect of gatifloxacin andciprofloxacin in the treatment of acute bacterial infections / 重庆医科大学学报

Objective:To evaluate the clinical efficacy and safety of gatifloxacin in the treatment of mild and moderate bacterial infections of respiratory tract,urinary tract,genital tract,skin and soft tissues.Methods:115 patients in study group were treated with gatifloxacin 200mg taken orally q12h,and 108 patients in control group were treated with ciprofloxacin 250mg taken orally q8h for 7days to 14 days.Results:The total cure rates of study group and control group were 90.4% and 77.8%( P 0.05),respectively.The bacterial eradication rates of the two groups were 97.1% and 89.2%( P 0.05),respectively.Conclusion:Gatifloxacin is a highly effective and well tolerated antibacterial agent for treatment of acute bacterial infections of respiratory tract,urinary tract,genital tract,skin and soft tissues.

A randomized comparative study on the effect of gatifloxacin and ciprofloxacin therapy in urinary tract and genital bacterial infections / 重庆医科大学学报

0.05),respectively.Sensitivity rate of 37 bacterial strains to gatifloxacin,ciprofloxacin,levofloxacin,sipafloxacin,cefataxime and penicillin(for gonococcus) were 100.0%,86.5%,94.6%,76.5%,91.9%,100.0%,respectively.Adverse events were generally mild,and adverse events rates of the two groups were 8.3% and 5.0%,respectively.Conclusion:Gatifloxacin is an highly effective and well tolerated antibacterial agent for the treatment of urinary tract and genital bacterial infections.