RESUMEN
In the history of modern medicine, the operating room has undergone a series of evolution since its origin. This article explains the etymology of operating theatre and illustrates the history of its origin and development. Transformed from anatomical amphitheatre and currently to surgical amphitheatre to modern operating room, the design purpose of operating room has changed from demonstration and teaching to elimination of infection and and to the pursuit of higher aseptic principles nowadays. The promotion of antisepsis and advent of anaesthesia changed the operating room in the past. In the future, the renewal of scientific ideas and technological progress will continue to promote the evolution of the form and content of the operating room and keep it moving towards medical humanism.