La Asimetría Cerebral, Retos para la Relación Neuropsicología y Educación / Brain Asymmetry, Relationship Challenges Neuropsychology and Education / Assimetria cerebral, desafios de relacionamento, neuropsicologia e educação

Resumen Introducción: El desarrollo de la neurociencia en relación a la educación ha sido desafiante y sus avances. Objetivo: Analizar hermenéutica y sistemática la línea de desarrollo teórico en artículos cualitativos y cuantitativos publicados entre los años 1999 y 2020 de las relaciones entre la asimetría cerebral dentro de las disciplinas: la neuropsicología y la educación. Materiales y métodos: Análisis hermenéutico desarrollado bajo el esquema de la interpretación de los textos primarios y secundarios, evaluados desde la rigurosidad de la hermenéutica en sus cuatro formas de evaluación: "fijación del discurso"; "disociación mental e intención del autor"; "muestra de las referencias no ostensivas" y "universalidad del documento: ¿A quién está dirigido?". Resultado: La investigación sobre las asimetrías cerebrales (funcionales y anatómicas), especialmente en cuanto al uso de la mano contraria (izquierda o derecha) a la de su lateralidad y su diseminación ha sido limitada e históricamente polarizada haciendo más énfasis en asimetrías cerebrales entendidas desde la influencia fisiológica neurológica y en muestra de resultados desde la actividad cerebral en neuroimágenes. Conclusión: La neuropsicología y la educación en su trabajo sobre las asimetrías cerebrales han estado relacionados a los conceptos médicos: anatomía y fisiología. La "nueva visión" y el surgimiento de especialidades como la neuropsicología, creando la necesidad de dar respuesta a los procesos de aprendizaje y las conexiones existentes entre una y otra.

Abstract Introduction: The development of neuroscience in relation to education has been challenging throughout its development. Objective: To analyze hermeneutically and systematically the line of theoretical development in qualitative and quantitative articles published between 1999 and 2020 of the relationships between brain asymmetry within the disciplines: neuropsychology and education. Materials and methods: Hermeneutical analysis developed under the scheme of the interpretation of primary and secondary texts, evaluated from the scientific rigurosity of hermeneutics in its four forms of evaluation: "discourse fixation"; "Mental dissociation and intention of the author"; "Sample of nonostentatious references'' and "universality of the document: Who is it addressed to?". Result: Research on brain asymmetries (functional and anatomical), especially regarding the use of the opposite hand (left or right) to its laterality and its dissemination has been limited and historically polarized, placing more emphasis on brain asymmetries understood from the neurological physiological influence and the sample of results from brain activity in neuro-images. Conclusion: Neuropsychology and education in their work on brain asymmetries have been related to medical concepts: anatomy and physiology. The "new vision" and the unfolding of specialties such as neuropsychology, creating the need to respond to the learning process and the existing connections between one and the other.

Resumo Introdução: O desenvolvimento da neurociência em relação à educação tem sido desafiador e seus avanços. O objetivo é analisar hermenêutica e sistematicamente a linha de desenvolvimento teórico em artigos qualitativos e quantitativos publicados entre 1999 e 2020 das relações entre assimetria cerebral nas disciplinas: neuropsicologia e educação. Materiais e Métodos: Análise hermenêutica desenvolvida sob o esquema da interpretação de textos primários e secundários, avaliada a partir do rigor da hermenêutica em suas quatro formas de avaliação: "fixação do discurso"; "Dissociação mental e intenção do autor"; "Amostra de referências não ostensivas" e "universalidade do documento: a quem se dirige?". Resultado: as pesquisas sobre assimetrias cerebrais (funcionais e anatômicas), principalmente quanto ao uso da mão oposta (esquerda ou direita) à sua lateralidade e sua disseminação tem sido limitada e historicamente polarizada, dando mais ênfase às assimetrias cerebrais entendidas a partir da influência fisiológica neurológica e a amostra de resultados da atividade cerebral em neuroimagens. Conclusão: a neuropsicologia e a educação em seu trabalho sobre as assimetrias cerebrais têm sido relacionadas aos conceitos médicos: anatomia e fisiologia. A "nova visão" e o surgimento de especialidades como a neuropsicologia, criando a necessidade de responder ao processo de aprendizagem e às ligações existentes entre um e outro.

Lateral visual hemifield asymmetry and sex differences in recognizing low and high spatial frequency filtered faces

The present study investigated whether low and high spatial frequency filtered images of faces were recognized differently when briefly presented in the right and the left visual fields of men and women. The method of confidence rating was applied to assess pooled Receiver Operating Characteristic curves based on z scores and the d´ parameter of Signal Detection Theory for recognition indices, in addition to response times. The results showed that men better recognized low spatial frequency filtered faces than high spatial frequency filtered faces in both visual fields, suggesting that both the right and left hemispheres in males prioritize low spatial frequencies to recognize faces. The results for women were similar to men only when the faces were shown in the left visual field. When the faces were presented in the right visual field, women better recognized high spatial frequency filtered faces, suggesting that the left hemisphere in females prioritizes high spatial frequencies, whereas the right hemisphere in females prioritizes low spatial frequencies to recognize faces...

Right cerebral hemisphere and central auditory processing in children with developmental dyslexia / El hemisferio cerebral derecho y el procesamiento auditivo central en ninos con dislexia del desarrollo

Objective We hypothesized that if the right hemisphere auditory processing abilities can be altered in children with developmental dyslexia (DD), we can detect dysfunction using specific tests. Method We performed an analytical comparative cross-sectional study. We studied 20 right-handed children with DD and 20 healthy right-handed control subjects (CS). Children in both groups were age, gender, and school-grade matched. Focusing on the right hemisphere’s contribution, we utilized tests to measure alterations in central auditory processing (CAP), such as determination of frequency patterns; sound duration; music pitch recognition; and identification of environmental sounds. We compared results among the two groups. Results Children with DD showed lower performance than CS in all CAP subtests, including those that preferentially engaged the cerebral right hemisphere. Conclusion Our data suggests a significant contribution of the right hemisphere in alterations of CAP in children with DD. Thus, right hemisphere CAP must be considered for examination and rehabilitation of children with DD. .

Objectivo Examinamos si las habilidades del procesamiento auditivo central (PAC) del hemisferio derecho se encuentran alteradas en niños con dislexia del desarrollo (DD), por medio de pruebas específicas. Método Realizamos un estudio comparativo transversal. Estudiamos 20 niños diestros con DD y 20 niños controles (C) sanos. Los niños de ambos grupos fueron pareados por edad, género y grado escolar. Utilizamos varias pruebas para medir alteraciones del PAC, tales como: determinación de patrones de frecuencia; duración del sonido; reconocimiento de tono musical e identificación de sonidos ambientales, enfatizando la contribución del hemisferio derecho. Comparamos los resultados entre los niños con DD y C. Resultados Los niños con DD mostraron menores puntuaciones que los C en todas las subpruebas del PAC, incluyendo aquellas que involucran preferencialmente al hemisferio cerebral derecho. Conclusión Los datos obtenidos sugieren una contribución significativa del hemisferio derecho para producir alteraciones del PAC en niños con DD. Por lo tanto, las PAC que involucran al hemisferio derecho deben ser consideradas en la evaluación y rehabilitación de niño s con DD. .

Assimetrias hemisféricas na percepção de expressões faciais: um estudo com a técnica de campo visual dividido / Hemispheric asymmetries on the perception of facial expressions: a divided visual field study / Asymétries hémisphériques dans la perception d'expressions faciales: un étude avec la technique de champ visuel divisé / Asimetrías hemisféricas en la percepción de expresiones faciales: una investigación con la técnica de campo visual dividido

Foram investigadas as diferenças hemisféricas na percepção de expressões faciais de alegria, tristeza, raiva e medo. Vinte e um voluntários (9H, 12M) participaram do experimento. Foi utilizada a técnica de estudo campo visual dividido com a apresentação de faces à esquerda e à direita do ponto de fixação nas condições: 1) face com emoção à esquerda e face neutra à direita; 2) face neutra à esquerda e face com emoção à direita; 3) face com emoção à direita e à esquerda; 4) face neutra à direita e à esquerda. Os participantes determinaram o lado em que havia sido apresentada a face que aparentava expressar mais emoção. As análises de tempo de resposta revelaram que tristeza e medo foram identificadas mais rapidamente no campo visual esquerdo, o que indicaria uma vantagem do hemisfério direito no reconhecimento dessas expressões. O reconhecimento de expressões negativas pelo hemisfério direito concorda parcialmente com a hipótese da valência.

Hemispheric differences on the perception of facial expressions of happiness, sadness, anger and fear were investigated. Twenty-one volunteers (9M, 12F) took part in the experiment. The divided visual field technique was used with the presentation of faces on the left and on the right side of the fixation point in the conditions: 1) emotional face on the left and neutral face on the right, 3) neutral face on the left and emotional face on the right; 3) emotional face on the right and on the left; 4) neutral face on the right and on the left. Participants determined the side on which the face seemed to show greater emotional intensity. Response time analysis revealed that sadness and fear were identified faster on the left visual field, suggesting an advantage of the right hemisphere on the recognition of those expressions. The recognition of negative expressions by the right hemisphere agrees partially with the valence hypothesis.

Les différences hémisphériques dans la perception d'expressions du visage de joie, tristesse, colère et peur, ont été investiguées. Vingt-et-un volontaires (9H, 12F) ont participé de l'expérience. La technique d'étude de champ visuel divisé a été utilisée avec la présentation de faces à droite et à gauche du point de fixation dans les conditions: 1) face avec émotion à droite et face neutre à gauche; 2) face neutre à droite et face avec émotion à gauche; 3) face avec émotion à droite et à gauche; 4) face neutre à droite et à gauche. Les participants ont déterminé le coté qui avait présenté la face que révélait plus d'émotion. Les analyses de temps de réponse ont montré que tristesse et peur ont été identifiés plus rapidement dans le champ visuel gauche, ce que indiquerait un avantage du hémisphère droit dans la reconnaissance de ces expressions. La reconnaissance d'expressions négatives par l'hémisphère droit est partiellement conforme à l'hypothèse de valence.

Fueron investigadas las diferencias hemisféricas en la percepción de expresiones faciales de alegría, tristeza, rabia y miedo. Veintiún voluntarios (9H, 12M) participaron del experimento. Fue usada la técnica de campo visual dividido con la presentación de rostros a la izquierda y a la derecha del punto de fijación en las condiciones: 1) rostro con emoción a la izquierda y rostro neutro a la derecha; 2) rostro neutro a la izquierda y rostro con emoción a la derecha; 3) rostro con emoción a la derecha y a la izquierda; 4) rostro neutro a la derecha y a la izquierda. Los participantes identificaran el lado en que había sido presentado el rostro que aparentaba tener más emoción. Los análisis del tiempo de respuesta revelaron que tristeza y miedo fueron identificadas más rápidamente en el campo visual izquierdo, lo que indicaría una ventaja del hemisferio derecho en el reconocimiento de estas expresiones. El reconocimiento de expresiones negativas por el hemisferio derecho concuerda parcialmente con la hipótesis de la valencia.

The ex-illiterate brain: the critical period, cognitive reserve and HAROLD model / O cérebro ex-analfabeto: o período crítico, reserva cognitiva e o modelo HAROLD

Abstract ? The lifelong acquisition of cognitive skills shapes the biology of the brain. However, there are critical periods for the best use of the brain to process the acquired information. Objectives: To discuss the critical period of cognitive acquisition, the concept of cognitive reserve and the HAROLD (Hemispheric Asymmetry Reduction in Older adults) model. Methods: Seven women who learned how to read and to write after the age of 50 (ex-illiterates) and five women with 10 years of regular schooling (controls) were submitted to a language recognition test while brain activity was being recorded using magnetoencephalography. Spoken words were delivered binaurally via two plastic tubs terminating in ear inserts, and recordings were made with a whole head magnetometer consisting of 148 magnetometer coils. Results: Both groups performed similarly on the task of identifying target words. Analysis of the number of sources of activity in the left and right hemispheres revealed significant differences between the two groups, showing that ex-illiterate subjects exhibited less brain functional asymmetry during the language task. Conclusions: These results should be interpreted with caution because the groups were small. However, these findings reinforce the concept that poorly educated subjects tend to use the brain for information processing in a different way to subjects with a high educational level or who were schooled at the regular time. Finally, the recruiting of both hemispheres to tackle the language recognition test occurred to a greater degree in the ex-illiterate group where this can be interpreted as a sign of difficulty performing the task.

Resumo ? A aquisição ao longo da vida de competências cognitivas moldam a biologia do cérebro. No entanto, existem períodos críticos para o cérebro processar melhor as informações adquiridas. Objetivos: Discutir o período crítico de aquisição cognitiva, o conceito de reserva cognitiva e o modelo HAROLD (Redução da Assimetria Hemisférica em Idosos). Métodos: Sete mulheres que aprenderam a ler e escrever após a idade de 50 anos (ex-analfabetos) e cinco mulheres com 10 anos de escolaridade regular (controles) foram submetidas a um teste de reconhecimento de palavras enquanto a atividade cerebral estava sendo registrada mediante magnetoencefalografia. As palavras foram ouvidas com o emprego de dois tubos plásticos conectados a cada orelha e as gravações foram feitas com um magnetômetro de cabeça inteira com 148 bobinas de registro. Resultados: Ambos os grupos tiveram desempenho semelhante na identificação das palavras-alvo. Análise do número de fontes de atividade no hemisfério esquerdo e no hemisfério direito revelou diferenças significativas entre os dois grupos, mostrando que os ex-analfabetos tiveram menor assimetria cerebral funcional no desempenho da tarefa. Conclusões: Estes resultados devem ser interpretados com cautela, pois os grupos são pequenos. No entanto, reforçam o conceito que os indivíduos com baixa escolaridade tendem a usar o cérebro para processar informações de uma forma diferente do que indivíduos com nível educacional elevado ou que tenham o adquirido na época regular. Finalmente, o recrutamento de ambos os hemisférios para reconhecer as palavras ocorreu mais intensamente no grupo de ex-analfabetos e pode ser interpretado como um sinal de maior dificuldade na tarefa.

Models of brain asymmetry in emotional processing

Two models of brain asymmetry in emotional processing were reviewed: the right hemisphere and the valence hypotheses. The first states a dominant role for the right hemisphere in emotional processing, whereas the second assumes that the left hemisphere is dominant for positive emotions and the right hemisphere for negative ones. Different methods, such as the divided visual field technique, have supported both hypotheses. The amygdala and the prefrontal cortex are presented as important structures involved on brain asymmetry in emotional processing. The paper ends pointing out new perspectives for the study of the neural subtrates of different components of emotions.

IL-1?,IL-6 levels and SOCS-3 gene expression in hypothalamus of BALB/c mice with brain asymmetry / 中国免疫学杂志

Objective:To investigate the effects of brain asymmetry on levels of IL-1?,IL-6 and suppressor of cytokine signaling-3(SOCS-3) in hypothalamus,to get better understanding of relationship between brain asymmetry and neuro-immuno-endocrine network at the molecular level.Methods:By using paw preference test,right-pawed,left-pawed,and ambidextrous mice model was established.After decapitation of the mice,hypothalamus was separated rapidly.Some samples were homogenized and used for detection of levels of interleukin-1?(IL-1?),interleukin-6(IL-6) by Enzyme-Linked-Immunosorbent Assay(ELISA).The other samples were applied to detect SOCS-3 expression level by RT-PCR.Results:(1)The level of IL-6 in hypothalamus:left-pawed were higher than right-pawed mice,there was significant difference in statistics( P 0.05).(3)The expression level of SOCS-3:the SOCS-3 expression of right-pawed showed higher than left-pawed mice in hypothalamus,revealing a significant difference( P